| GNAZ | guanosine nucleotide-binding alpha Z polypeptide |
|---|---|
| GSH | glomerulus-stimulating hormone; golden Syrian hamster; reduced glutathione; L-alpha-glutamyl-L-cyste... |
| GSTA | glutathione-S-transferase, alpha |
| HAFP | human alpha-fetoprotein |
| HNF1A | hepatocyte nuclear factor-1-alpha |
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| interferon-alpha | <cytokine> One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded RNA, or bacterial products. It is the major interferon produced by virus-induced leukocyte cultures and, in addition to its pronounced antiviral activity, causes activation of NK cells. It is used experimentally in the treatment of hairy-cell leukaemia. A number of different subtypes exist that are elaborated by leukocytes in response to viral infection or stimulation with double-stranded RNA; IFN-alpha-2A and -2B are protein products made by recombinant DNA techniques and are used as antineoplastic agents. See: interferon-alpha 2a, interferon-alpha 2b Synonym: leukocyte interferon. Pharmacological action: antineoplastic agent, antiviral agent. (20 Sep 2002) |
|---|---|
| interferon-alpha 2a | <cytokine> Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. Pharmacological action: antineoplastic agent, antiviral agents. Chemical name: Interferon-alphaA (human leukocyte protein moiety reduced) (12 Dec 1998) |
| interferon-alpha 2b | <chemical> Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. Pharmacological action: antineoplastic agent, antiviral agents. (12 Dec 1998) |
| testosterone 15-alpha hydroxylase | <enzyme> A haem-thiolate protein (cytochrome p-450) Registry number: EC 1.14.15.- Synonym: cytochrome p-450(15alpha), testosterone 15-alpha monooxygenase, steroid 15-alpha-hydroxylase, cytochrome p-4502a-4, cyp2a-4, cyp2a4 (26 Jun 1999) |
| testosterone 5-alpha-reductase | <enzyme> Chemical name: 3-Oxo-5 alpha-steroid:(acceptor) delta(4)-oxidoreductase Registry number: EC 1.3.99.5 (12 Dec 1998) |
| TM-1 alpha-fibrinogenase | <enzyme> Isolated from the venom of taiwan habu, trimeresurus mucrosqamatus Registry number: EC 3.4.24.- (26 Jun 1999) |
| TM-2 alpha-fibrinogenase | <enzyme> Isolated from the venom of taiwan habu, trimeresurus mucrosquamatus Registry number: EC 3.4.24.- (26 Jun 1999) |
| TM-3 alpha-fibrinogenase | <enzyme> Isolated from the venom of taiwan habu, trimeresurus mucrosquamatus Registry number: EC 3.4.24.- (26 Jun 1999) |
| endo-1,3-alpha-glucanase | <enzyme> Endohydrolysis of 1,3-alpha-d-glucosidic linkages in isolichenin, pseudonigeran and nigeran; may also be called mutanase, see EC 3.2.1.84 exo-1,3-alpha-glucanase Registry number: EC 3.2.1.59 Synonym: endo-1,3-alpha-d-glucanase, endo-alpha-1,3-glucanase (26 Jun 1999) |
| endo-alpha-D-mannosidase | <enzyme> Catalyses the cleavage of glc(1)man(9)glcnac to yield man(8)glcnac and glcalpha1-3man Registry number: EC 3.2.1.- (26 Jun 1999) |
| transforming growth factor alpha | Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to epidermal growth factor (epidermal growth factor-urogasterone) and binds to the egf receptor. Tgf-alpha acts synergistically with tgf-beta in inducing phenotypic transformation, but its physiological role is unknown. (12 Dec 1998) |
| error, alpha | The statistical error (said to be of the first kind or type I) made in testing an hypothesis when it is concluded that a treatment or intervention is effective when it really is not. Sometimes referred to as a false positive. (12 Dec 1998) |
| estradiol 15 alpha-hydroxylase | <enzyme> Catalyses the conversion of estradiol to 15alpha-hydroxyestradiol Registry number: EC 1.14.99.- Synonym: e15a-hydroxylase (26 Jun 1999) |
| estradiol 16 alpha-hydroxylase | <enzyme> Cyp2c11 is a male-specific cyp isoform Registry number: EC 1.14.99.- Synonym: 16 alpha-hydroxylase, estrone 16 alpha-hydroxylase, 16alpha-hydroxylase, steroid 16 alpha-hydroxylase, estrone 3-sulfate 16 alpha-hydroxylase, cytochrome p450cmf, cytochrome p450 2c, cytochrome p450iic11, cytochrome p450(ut-a), cytochrome p4502c-rml5, cytochrome p450h, cytochrome p450(male), cytochrome p4502c, cytochrome p450 2c3, cytochrome p450 2c9, oestrogen 16-hydroxylase, cyp2c3 gene product, cyp2c11 gene product, cytochrome p450 2c11, cyp 2d-9, cytochrome p450(tb), cyp2c9, cytochrome p-450(m1), cyp2c11 (26 Jun 1999) |
| ethinylestradiol-17 alpha sulfotransferase | <enzyme> Responsible for the sulphation of 17 alpha-ethinylestradiol; found in human liver cytosol; mol mass 33-kD; not a phenol- or monoamine-sulphating phenolsulphotransferase nor a hydroxysteroid sulphotransferase Registry number: EC 2.8.2.- Synonym: 17 alpha-ethinyloestradiol sulphotransferase, ee(2) st, ee2 st (26 Jun 1999) |
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