| ACE | acetonitrile; acetylcholine esterase; acute cerebral encephalopathy; acute coronary event; adrenocor... |
|---|---|
| ACS | acrocallosal syndrome; acrocephalosyndactyly; acute chest syndrome; acute confusional state; Alcon C... |
| ADS | acute death syndrome; acute diarrheal syndrome; Alcohol Dependence Scale; alternative delivery syste... |
| AHC | academic health care; academic health center; acute hemorrhagic conjunctivitis; acute hemorrhagic cy... |
| AHE | acute hazardous events [database]; acute hemorrhagic encephalomyelitis |
| leukaemia, erythroblastic, acute | A myeloproliferative disorder characterised by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood. (12 Dec 1998) |
|---|---|
| leukaemia, megakaryocytic, acute | Nonlymphocytic leukaemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. Myelofibrosis or increased bone marrow reticulin is common. (12 Dec 1998) |
| leukaemia, myelocytic, acute | Progressive, malignant disease of the myeloid tissue in which the granular, polymorphonuclear leukocytes and their precursors predominate. (12 Dec 1998) |
| leukaemia, nonlymphocytic, acute | Acute leukaemia distinguished from acute lymphocytic leukaemia (all) by the morphology of the marrow and blood leukaemic cells. Cytoplasmic granules are usually present and the nucleus is usually large and irregular. Anll is more common in adults than all and occurs at any age. (12 Dec 1998) |
| leukoencephalitis, acute haemorrhagic | A rare, fatal postinfection or allergic demyelinating disease of the central nervous system having a fulminating course and occurring mainly in young adults. It is characterised by destruction of white matter to the point of liquefaction; widespread necrosis of blood vessel walls leading to the formation of multiple small haemorrhages in the involved areas and the exudation of fibrin into the surrounding tissue; and cellular infiltration of the necrotic areas. (12 Dec 1998) |
| liver failure, acute | A form of liver failure with rapid onset. It is often induced by the toxic effect of drugs and various toxic substances in experimental studies in animals and in clinical states in humans. If coma ensues, the constellation of neurological symptoms is referred to as hepatic encephalopathy. (12 Dec 1998) |
| acetone-insoluble antigen | A diphosphatidyl glycerol that is found in the membrane of Treponema pallidum and is the antigen detected by the Wasserman test for syphilis. (18 Nov 1997) |
| allogeneic antigen | Genetic variations of the same antigens within a given species. (05 Mar 2000) |
| antigen | Virus coded cell surface antigens that appear soon after the infection of a cell by virus, but before virus replication has begun. See: early gene. (18 Nov 1997) |
| antigen-antibody complex | The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes immune complex diseases. If the antigen is polyvalent the complex may be insoluble. Immune complexes activate complement through the classical pathway. See: glomerulonephritis, Arthus reaction, type III hypersensitivity. (12 Dec 1998) |
| antigen-antibody reaction | The phenomenon, occurring in vitro or in vivo, of antibody combining with antigen of the type that stimulated the formation of the antibody, thereby resulting in agglutination, precipitation, complement fixation, greater susceptibility to ingestion and destruction by phagocytes, or neutralization of exotoxin. See: skin test. (05 Mar 2000) |
| antigen-binding site | <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope). Also used of the site on a ligand molecule to which a cell surface receptor binds. (18 Nov 1997) |
| antigen-combining site | See: paratope. (05 Mar 2000) |
| antigen excess | In a precipitation test, the presence of uncombined antigen above that required to combine with all of the antibody; precipitation may be inhibited because the presence of excess antigen gives rise to soluble antigen-antibody complexes, in vivo the resultant antigen-antibody interaction in such an antigen excess may give rise to immune complexes, which have a potential to induce cellular damage; such injury underlies the pathologic changes seen in certain immune complex diseases. (05 Mar 2000) |
| antigen interferon | <cytokine> Interferon elaborated by T lymphocytes in response to either specific antigen or mitogenic stimulation. This type II interferon can be produced by recombinant DNA technology and is similar to the interferon secreted by lymphocytes and has antiviral and antineoplastic activity. Synonym: antigen interferon, immune interferon. Pharmacological action: antineoplastic agent, antiviral agents. (20 Sep 2002) |