| Cushing's basophilism | <endocrinology, syndrome> An increased concentration of glucocorticoid hormone (ACTH) in the bloodstream that is being produced by an adrenal gland tumour (adenoma). Ectopic Cushing syndrome refers to the production of ACTH in a location other than the pituitary gland or adrenal gland. Examples of ectopic sites include thymoma, medullary carcinoma of the thyroid, pheochromocytoma, islet cell tumours of the pancreas and oat cell carcinoma of the lung. Symptoms include weight gain, central obesity, moon face, weakness, fatigue, backache, headache, increased thirst, increased urination, impotence, mental status changes and muscle atrophy. Treatment varies with cause. If an ACTH secreting tumour is involved then it must be removed surgically. (27 Sep 1997) |
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| Cushing's disease | <disease> An increased concentration of glucocorticoid hormone in the bloodstream (produced by the adrenal gland) secondary to a pituitary tumour that is secreting the hormone adrenocorticotropic hormone (ACTH). ACTH serves to stimulate the adrenal gland to produce excess glucocorticoids. (27 Sep 1997) |
| Cushing's pituitary basophilism | <disease> An increased concentration of glucocorticoid hormone in the bloodstream (produced by the adrenal gland) secondary to a pituitary tumour that is secreting the hormone adrenocorticotropic hormone (ACTH). ACTH serves to stimulate the adrenal gland to produce excess glucocorticoids. (27 Sep 1997) |
| Cushing's suture | A running horizontal mattress suture used to approximate two adjacent surfaces. (05 Mar 2000) |
| Cushing's syndrome | <endocrinology, syndrome> An increased concentration of glucocorticoid hormone (ACTH) in the bloodstream that is being produced by an adrenal gland tumour (adenoma). Ectopic Cushing syndrome refers to the production of ACTH in a location other than the pituitary gland or adrenal gland. Examples of ectopic sites include thymoma, medullary carcinoma of the thyroid, pheochromocytoma, islet cell tumours of the pancreas and oat cell carcinoma of the lung. Symptoms include weight gain, central obesity, moon face, weakness, fatigue, backache, headache, increased thirst, increased urination, impotence, mental status changes and muscle atrophy. Treatment varies with cause. If an ACTH secreting tumour is involved then it must be removed surgically. (27 Sep 1997) |
| Cushing's syndrome medicamentosus | A variable number of the signs and symptoms of Cushing's syndrome; produced by the chronic administration of large doses of any steroid that is a potent glucocorticoid. (05 Mar 2000) |
| Cushing, Harvey | <person> This leader of neurosurgery was born in Cleveland, Ohio, graduated from Harvard in 1895, remained at Massachusetts General Hospital for one year, spent 15 years at Johns Hopkins, returned to Harvard as Professor of Surgery, and retired in new Haven where he continued actively until his death. Cushing's accomplishments in neurosurgery were amazing. In 1906, he demonstrated the relationship between pituitary tumours and sexual infantilism. In 1917, he published a classic, "The Pituitary Body and Its Disorders." Cushing wrote many charming essays, some of which were published as a collection under the title, "Consecratio Medici" in 1928. He was an earnest collector of books and bequeathed his valuable collection to the Yale Library. Among his many publications were a Biography of 0sler, and a Biography of Andreas Vesalius. Lived: 1869-1939. (15 Nov 1997) |
| Cushing, Hayward | <person> U.S. Surgeon, 1854-1934. See: Cushing's suture. (05 Mar 2000) |
| cushingoid | Resembling the signs and symptoms of Cushing's disease or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to exogenous corticosteroids. (05 Mar 2000) |
| cushion | <botany> A swollen floral stem on which several small flowers are borne. (13 Nov 1997) |
| cushion of epiglottis | A convexity at the lower part of the epiglottis over the upper part of the thyroepiglottic ligament. Synonym: tuberculum epiglotticum, cushion of epiglottis. (05 Mar 2000) |
| cusp | A rigid, sharp point, especially on a leaf. (09 Oct 1997) |
| cusp angle | The angle made by the slopes of a cusp with the plane which passes through the tip of the cusp and which is perpendicular to a line bisecting the cusp, measured mesiodistally or buccolingually, the angle made by the slopes of a cusp with a perpendicular line bisecting the cusp, measured mesiodistally or buccolingually, one-half of the included angle between the buccal and lingual or mesial and distal cusp inclines. (05 Mar 2000) |
| cusp height | The shortest distance between the tip of a cusp and its base plane, the shortest distance between the deepest part of the central fossa of a posterior tooth and a line connecting the points of the cusps of the tooth. Facial height, the linear dimension in the midline from the hairline to the menton. Nasal height, the distance between the nasion and the lower border of the nasal aperture. Orbital height, the distance between the midpoints of the upper and lower margins of the orbit. (05 Mar 2000) |
| cusp of Carabelli | A fifth cusp found on the maxillary first molars, usually located lingual to the mesiolingual cusp. (05 Mar 2000) |