| gitter cell | A lipid-laden microglial phagocyte commonly seen at the edge of healing brain infarcts, a result of cellular phagocytosis of lipid from necrotic or degenerating brain cells. Synonym: compound granule cell. Origin: Ger. Gitterzelle, fr. Gitter, lattice, wire-net (05 Mar 2000) |
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| M cell | <cell biology> An autonomous self replicating unit (in principle) that may constitute an organism (in the case of unicellular organisms) or be a sub unit of multicellular organisms in which individual cells may be more or less specialised differentiated) for particular functions. The individual units from which tissues of the body are formed. All living organisms are composed of one or more cells. (26 Mar 1998) |
| regulatory cell proliferation kinase | <enzyme> Involved in mitosis regulation; has characteristics of serine/threonine and tyrosine kinases; isolated from saccharomyces cerevisiae; genbank l08909 Registry number: EC 2.7.1.- Synonym: rpk1 protein, rpk1 gene product (26 Jun 1999) |
| regulatory T-cell | <immunology> Vague term for any class of T lymphocyte not directly involved in the effector side of immunity, but involved in controlling responses and actions of other cells, especially T helper and T suppressor cells. (18 Nov 1997) |
| glial cell | <pathology> Specialised cells that surround neurons, providing mechanical and physical support and electrical insulation between neurons. (17 Dec 1997) |
| C cell | A cell of the pancreatic islets of the guinea pig. Synonym: gamma cell of pancreas. Synonym: parafollicular cells. (05 Mar 2000) |
| globe cell anaemia | <haematology> A hereditary disorder that leads to a chronic haemolytic anaemia due to an abnormality in the red blood cell membrane. This disorder is caused by a defective gene. Red cells are resistant to stress and rupture easily. Infants may appear jaundiced and pale. Fatigue, weakness and shortness of breath are other symptoms that may be seen in older patients. The spleen may also be enlarged. Treatment includes splenectomy (removal of the spleen). After this is accomplished the life-span of the red blood cells returns to normal. (27 Sep 1997) |
| globoid cell | A large cell of mesodermal origin that is found clustered in the intracranial tissues in globoid cell leukodystrophy. (05 Mar 2000) |
| globoid cell leukodystrophy | <radiology> Dysmyelinating disease, autosomal recessive, usually presents by 1 yr, specific enzyme deficiency identified, rapid spontaneous nystagmus, poikilothermia Synonym: Krabbe leukodystrophy (12 Dec 1998) |
| CD4 cell | T helper cells which are targets for HIV infection. (09 Oct 1997) |
| CD4 cell count | The most commonly used surrogate marker for assessing the state of the immune system. As CD4 cell count declines, the risk of developing opportunistic infections increases. The normal range for CD4 cell counts is 500 to 1500 per cubic millimetre of blood. CD4 count should be rechecked at least every six to twelve months if CD4s are greater than 500/mm3. If the count is lower, testing every three months is advised. (09 Oct 1997) |
| virus-transformed cell | A cell that has been genetically changed to a tumour cell, the change being subsequently tramsmitted to all descendent cell's; cell's transformed by oncornaviruses continue to produce virus in high concentration without being killed; DNA tumour virus-transformed cell's develop (along with other changes) tumour-associated antigens and rarely produce virus. (05 Mar 2000) |
| glomerulosa cell | A cell of the zona glomerulosa of the adrenal cortex that is the source of aldosterone; the cell's are arranged in spherical or oval groups. (05 Mar 2000) |
| cell | <cell biology> An autonomous self replicating unit (in principle) that may constitute an organism (in the case of unicellular organisms) or be a sub unit of multicellular organisms in which individual cells may be more or less specialised differentiated) for particular functions. The individual units from which tissues of the body are formed. All living organisms are composed of one or more cells. (26 Mar 1998) |
| cell adhesion | See: adhesins, cadherins, cell adhesion molecules (CAMs), contact sites A, DLVO theory, integrins, sorting out, uvomorulin and various specialised junctions (adherens junctions, desmosomes, focal adhesions, gap junction and zonula occludens). (18 Nov 1997) |