| dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase | <enzyme> Catalyses the transfer of mannose from dolichyl-p-mannose to the man(5)(glcnac)2-pp-dolichol acceptor glycolipid Registry number: EC 2.4.1.130 Synonym: dolichyl-p-mannose-dolichyl-pp-heptasaccharide alpha-mannosyltransferase, dolichyl-p-mannose-man(5)(glcnac)2-pp-dolichol mannosyltransferase, dpm-g-mannosyltransferase (26 Jun 1999) |
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| D-selenocystine alpha, beta-lyase | <enzyme> From clostridium sticklandii; pyridoxal-p enzyme; mw 74kda; decomposes d-selenocystine into pyruvate, nh3 and elemental selenium; d-cystine, d-lanthionine, meso-lanthionine and d-cysteine can also serve as substrates; d-selenocysteine, d-serine, dl-selenohomocystine and l-amino acids are inert Registry number: EC 4.99.- Synonym: dsc-ab-lyase (26 Jun 1999) |
| I kappa B alpha-associated protein kinase | <enzyme> Isolated from human monocytic cell line; phosphorylates ser(293), ser(288), and thr(291) of ikappabalpha Registry number: EC 2.7.10.- Synonym: ikappabalpha-associated protein kinase, ikappab-alpha-associated protein kinase, ikappabalpha kinase (26 Jun 1999) |
| immunoglobulins, alpha-chain | Heavy chains found in the fab and fc fragments of IgA and having a molecular weight of approximately 58 kD. They contain about 470 amino acid residues arranged in four domains and an oligosaccharide component bound covalently to the fc fragment. (12 Dec 1998) |
| indolyl-3-alkane-alpha-hydroxylase | <enzyme> Indoyl-3-alkane-alpha-hydroxylase; haemprotein which needs no cofactor Registry number: EC 1.13.99.- Synonym: tryptophan side chain oxidase (26 Jun 1999) |
| inositol 1-alpha-galactosyltransferase | <enzyme> Catalyses conversion of udpgalactose plus myo-inositol to galactinol plus udp Registry number: EC 2.4.1.123 Synonym: galactinol synthase (26 Jun 1999) |
| inter-alpha-inhibitor | <chemical> Inhibits bovine trypsin and chymotrypsin; complex formed with chymotrypsin less stable; alpha-glycoprotein; shap - serum-derived hyaluronan associated protein Pharmacological action: serine proteinase inhibitors, trypsin inhibitors Chemical name: trypsin inhibitor, inter-alpha- Synonym: inter-alpha-trypsin inhibitor, protein pi, inter-alpha-trypsin inhibitor, heavy chain, shap protein (05 Dec 1998) |
| interferon-alpha | <cytokine> One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded RNA, or bacterial products. It is the major interferon produced by virus-induced leukocyte cultures and, in addition to its pronounced antiviral activity, causes activation of NK cells. It is used experimentally in the treatment of hairy-cell leukaemia. A number of different subtypes exist that are elaborated by leukocytes in response to viral infection or stimulation with double-stranded RNA; IFN-alpha-2A and -2B are protein products made by recombinant DNA techniques and are used as antineoplastic agents. See: interferon-alpha 2a, interferon-alpha 2b Synonym: leukocyte interferon. Pharmacological action: antineoplastic agent, antiviral agent. (20 Sep 2002) |
| interferon-alpha 2a | <cytokine> Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. Pharmacological action: antineoplastic agent, antiviral agents. Chemical name: Interferon-alphaA (human leukocyte protein moiety reduced) (12 Dec 1998) |
| interferon-alpha 2b | <chemical> Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. Pharmacological action: antineoplastic agent, antiviral agents. (12 Dec 1998) |
| testosterone 15-alpha hydroxylase | <enzyme> A haem-thiolate protein (cytochrome p-450) Registry number: EC 1.14.15.- Synonym: cytochrome p-450(15alpha), testosterone 15-alpha monooxygenase, steroid 15-alpha-hydroxylase, cytochrome p-4502a-4, cyp2a-4, cyp2a4 (26 Jun 1999) |
| testosterone 5-alpha-reductase | <enzyme> Chemical name: 3-Oxo-5 alpha-steroid:(acceptor) delta(4)-oxidoreductase Registry number: EC 1.3.99.5 (12 Dec 1998) |
| TM-1 alpha-fibrinogenase | <enzyme> Isolated from the venom of taiwan habu, trimeresurus mucrosqamatus Registry number: EC 3.4.24.- (26 Jun 1999) |
| TM-2 alpha-fibrinogenase | <enzyme> Isolated from the venom of taiwan habu, trimeresurus mucrosquamatus Registry number: EC 3.4.24.- (26 Jun 1999) |
| TM-3 alpha-fibrinogenase | <enzyme> Isolated from the venom of taiwan habu, trimeresurus mucrosquamatus Registry number: EC 3.4.24.- (26 Jun 1999) |