| succinylacetoacetate |
a compound formed by reduction of fumarylacetoacetate; it occurs at elevated levels in tyrosinemia, type I, due to the deficiency of fumarylacetoacetase. It is readily decarboxylated to succinylacetone (q.v.); both compounds can cause hepatorenal damage.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| succinylacetone |
the compound formed by decarboxylation of succinylacetoacetate, occurring at elevated levels in tyrosinemia, type I, and believed to cause the characteristic hepatorenal damage. It competitively inhibits porphobilinogen synthase by being a structural analog of δ-aminolevulinic acid, secondarily inhibits other enzymes of tyrosine metabolism, and is structurally similar to maleic acid, an inhibitor of renal tubular function.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| succinyldihydrolipoamide |
succinyl bound to lipoamide, an intermediate in the reaction catalyzed by the α-ketoglutarate dehydrogenase complex.
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| succorrhea |
an excessive flow of a juice or secretion, as in ptyalism.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| succussion s.’s |
splashing sounds heard over a distended stomach or in hydropneumothorax during succussion. Called also hippocratic s's.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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