| Rayer's disease | Xanthomatosis with hypercholesterolaemia, resulting from biliary cirrhosis. Synonym: Rayer's disease. (05 Mar 2000) |
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| Raynaud's disease | <disease> Paroxysmal spasm of the digital arteries causing pallor (blanching) of the fingers and toes. Maurice Raynaud, French physician (1834-81). (27 Sep 1997) |
| veno-occlusive disease | <haematology, oncology> A disease that sometimes occurs following high-dose chemotherapy or radiation, in which the blood vessels that carry blood through the liver become swollen and clogged. Acronym: VOD (12 Jan 1998) |
| veno-occlusive disease of the liver | Obliterating endophlebitis of small hepatic vein radicles, described in Jamaican children, associated with ingestion of toxic plant substances in bush tea; causes ascites, which may progress to cirrhosis. (05 Mar 2000) |
| maple bark disease | <radiology> Type of extrinsic allergic alveolitis, source: moldy maple bark in saw mills, organism: Cryptostroma corticale (12 Dec 1998) |
| maple syrup urine disease | Hereditary disease due to deficiency of an enzyme involved in amino acid metabolism, characterised by urine that smells like maple syrup. (12 Dec 1998) |
| marble bone disease | The formation of abnormally dense bone, as opposed to osteoporosis. (18 Nov 1997) |
| genetic disease | <biology, genetics> A disease, such as cystic fibrosis, that has its origin in changes to the genetic material, DNA. Usually refers to diseases that are inherited in a Mendelian fashion, although noninherited forms of cancer also result from DNA mutation. (07 May 1998) |
| Marburg disease | Infection with an unusual rhabdovirus composed of RNA and lipid, tentatively assigned to the family of Filoviridae. Virus is "pantropic" and affects most organ systems.The disease is characterised by a prominent rash and haemorrhages in many organs and is often fatal. First seen among laboratory workers in Marburg, Germany, exposed to African green monkeys. Some person-to-person spread has been observed. Attempts to isolate virus should be done only in high-security laboratories. Synonym: Marburg virus disease. (05 Mar 2000) |
| marburg virus disease | An RNA virus infection of rhesus, vervet, and squirrel monkeys transmissible to man. (12 Dec 1998) |
| marchiafava-bignami disease | <radiology> Italian wine-drinkers' disease, symmetric demyelinization: corpus callosum, white matter, anterior commisure (12 Dec 1998) |
| Marek disease | <disease> Infectious cancer of the lymphoid system (lymphomatosis) in chickens, caused by a contagious Herpes virus. An effective vaccine is now available. (18 Nov 1997) |
| marek's disease | A lymphoproliferative disease of fowl caused by a herpes virus. Lymphoid cell infiltrations are most common in the peripheral nerves and gonads, but widespread infiltrations may also be found in any of the visceral organs, skin, muscle, and the iris of the eye. The location of the lesions dictates the clinical signs, such as paralysis, general depression, and blindness. (12 Dec 1998) |
| Marek's disease virus | The herpesvirus that causes avian lymphomatosis (Marek's disease); is distinct from those causing other forms of leukosis. Synonym: avian lymphomatosis virus, fowl neurolymphomatosis virus, Marek's disease virus. (05 Mar 2000) |
| Marfan's disease | <syndrome> A hereditary condition of the connective tissue. Symptoms and signs include tall lean body type, irregular or unsteady gait, long extremities (including fingers and toes), abnormal joint flexibility, flat feet, stooped shoulders, dislocation of the optic lens and aneurysms of the aorta. Affects 1 in 50,000 people. Probably a collagen fibril assembly disorder since it can be mimicked in mice by aminonitriles that interfere with crosslinking. Inheritance: autosomal dominant. (06 Oct 1997) |