| carcinoid tumour | A tumour which secretes excessive amounts of the hormone serotonin. The clinical result is carcinoid syndrome. These tumours may grow anywhere in the gastrointestinal tract (and in the lungs) with approximately 90% in the appendix. The remainder occur in the ileum, stomach, colon or rectum. (27 Sep 1997) |
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| carcinoma, ehrlich tumour | A transplantable, poorly differentiated malignant tumour which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. (12 Dec 1998) |
| p60 tumour necrosis factor receptor-associated kinase | <enzyme> Interacts with and causes phosphorylation of the cytoplasmic domain of the tnf receptor Registry number: EC 2.7.10.- Synonym: p60 tnf receptor-associated kinase, p60-trak (26 Jun 1999) |
| pancoast tumour | <oncology, tumour> Tumour originating from the superior sulcus of the lung that invades all or a portion of the brachial plexus. (16 Dec 1997) |
| malignant giant cell tumour | A type of bone tumour. (12 Dec 1998) |
| malignant mixed mullerian tumour | A sarcoma of the body of the uterus arising in older women, composed of more than one mesenchymal tissue, especially including striated muscle cells. Synonym: malignant mixed mullerian tumour. (05 Mar 2000) |
| malignant tumour | A mass of cancer cells. These cells have uncontrolled growth and will invade surrounding tissues and spread to distant sites of the body, setting up new cancer sites, a process called metastasis. (09 Oct 1997) |
| papillary tumour | A tumour shaped like a small mushroom with its stem attached to the inner lining of the bladder. (12 Dec 1998) |
| mammary tumour virus | <organism, virology> Retrovirus that induces mammary carcinoma in mice. Isolated from highly inbred strains that had very high incidence of the tumours, after the discovery that the disease was transmitted by nursing mothers in milk. Endogenous provirus present in germ line of all inbred mice. Transcription of the provirus is regulated by a viral promoter that increases transcription in response to glucocorticoid hormones. May transform by proviral insertion activating the cellular int 1 oncogene (18 Nov 1997) |
| mammary tumour viruses, mouse | The type species of mammalian type b retroviruses (retroviruses type b, mammalian) commonly latent in mice. It causes mammary adenocarcinoma when in a genetically susceptible strain of mice and when the appropriate hormonal influences operate. (12 Dec 1998) |
| mammary tumour virus of mice | Member of the retrovirus subfamily Oncornavirinae, antigenically distinct from the murine leukaemia-sarcoma complex, that is associated with adenocarcinomatous tumours of the mammary gland, commonly latent in wild and laboratory mice and causing cancer only in genetically susceptible strains under certain hormonal influences. Synonym: Bittner agent, Bittner virus, Bittner's milk factor, mammary cancer virus of mice, milk factor, mouse mammary tumour virus. (05 Mar 2000) |
| ranine tumour | <medicine> A cyst formed under the tongue by obstruction of the duct of the submaxillary gland. Origin: L, a little frog, a little swelling on the tongue of cattle, dim. Of rana a frog. Source: Websters Dictionary (01 Mar 1998) |
| paraffin tumour | A tumefaction, usually a granuloma, caused by the prosthetic or therapeutic injection of paraffin into the tissues; sometimes used with reference to similar lesions resulting from the injection of any oil, wax, or the like. See: lipogranuloma. Synonym: paraffin tumour. (05 Mar 2000) |
| Rathke's pouch tumour | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
| genes, suppressor, tumour | Genes that inhibit expression of the tumourigenic phenotype. They are normally involved in holding cellular growth in check. When tumour suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (12 Dec 1998) |