| lactose i., congenital |
1. lactose intolerance present at birth, due to deficiency of lactase activity; see lactase deficiency. 2. a severe autosomal dominant disorder with vomiting, dehydration, failure to thrive, disacchariduria (including lactosuria and aminoaciduria), and cataracts; it is probably due to abnormal permeability of the gastric mucosa.
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| lactose synthase |
[EC 2.4.1.22] an enzyme of the transferase class that catalyzes the transfer of galactose from UDPgalactose to glucose, forming lactose. The enzyme is a complex of the enzyme glycoprotein 4-β-galactosyltransferase (q.v.) and α-lactalbumin; the latter protein is present in lactating mammary gland cells, where it alters the usual specificity of the former to make lactose synthesis the preferred reaction.
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| lactoside |
a glycoside whose sugar constituent is lactose.
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| lactosylceramide |
any of the glycosphingolipids in which the head group on the ceramide is lactose; they occur at low concentrations in all tissues.
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| lactotoxin |
a toxic substance formed in milk.
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