| haematoplast | <anatomy> Same as Haematoblast. Origin: Haemato- + Gr. To mold. Source: Websters Dictionary (01 Mar 1998) |
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| haematoplastic | <physiology> Blood formative; applied to a substance in early foetal life, which breaks up gradually into blood vessels. Origin: Haemato- + -plastic. Source: Websters Dictionary (01 Mar 1998) |
| haematopoiesis | <haematology> The formation and development of blood cells involving both proliferation and differentiation from stem cells. In adult mammals usually occurs in bone marrow. (18 Nov 1997) |
| haematopoiesis, extramedullary | The formation and development of blood cells outside the bone marrow, as in the spleen, liver, or lymph nodes. (12 Dec 1998) |
| haematopoietic | <pharmacology> Refers to an agent or process that affects or promotes the formation of blood cells. (09 Oct 1997) |
| haematopoietic cell growth factors | These growth factors comprise a family of haematopoietic regulators with biological specificities defined by their ability to support proliferation and differentiation of blood cells of different lineages. Erythropoietin and the colony-stimulating factors belong to this family. Some of these factors have been studied and used in the treatment of chemotherapy-induced neutropenia, myelodysplastic syndromes, and bone marrow failure syndromes. (12 Dec 1998) |
| haematopoietic cell phosphatase | <enzyme> Gene found on chromosome 12p12-p13 in motheaten (me) and viable motheaten mice; shp1 is product of me gene; a single base pair change creates or alters splicing signal sequences of hc phosphatase genes with consequent abnormal mRNA splicing and expression of aberrant hc phosphatase transcript; partial aa sequence given in first source Registry number: EC 3.1.3.- Synonym: hc phosphatase, haematopoietic cell phosphatase, hcph gene product, human haematopoietic tyrosine phosphatase, heptp, leukocyte protein-tyrosine phosphatase, lc-ptp, shp1 tyrosine tyrosine phosphatase, ptp-1c, protein tyrosine phosphatase 1c (26 Jun 1999) |
| haematopoietic gland | A blood-forming organ, such as the spleen. (05 Mar 2000) |
| haematopoietic stem cell mobilization | The release of stem cells from the bone marrow into the peripheral blood circulation for the purpose of leukapheresis, prior to stem cell transplantion. Haematopoietic growth factors or chemotherapeutic agents often are used to stimulate the mobilization. (12 Dec 1998) |
| haematopoietic stem cell transplantation | The transference of stem cells from one animal or human to another (allogeneic), or within the same individual (autologous). The source for the stem cells may be the bone marrow or peripheral blood. Stem cell transplantation has been used as an alternative to autologous bone marrow transplantation in the treatment of a variety of neoplasms. (12 Dec 1998) |
| haematopoietic stem cells | Progenitor cells from which all blood cells derive. (12 Dec 1998) |
| haematopoietic system | The blood-making organs; in the embryo at different ages these are the yolk sac, liver, thymus, spleen, lymph nodes, and bone marrow; after birth they are principally the bone marrow, spleen, thymus, and lymph nodes. (05 Mar 2000) |
| haematopoietin | <growth factor, hormone> Erythropoietin is a Glycoprotein (46 kD) hormone produced by specialised cells in the kidneys that regulates the production of red blood cells in the marrow. These cells are sensitive to low arterial oxygen concentration and will release erythropoietin when oxygen is low. Erythropoietin stimulates the bone marrow to produce more red blood cells (to increase the oxygen caring capacity of the blood). The measurement of this hormone in the bloodstream can indicate bone marrow disorders or kidney disease. Normal levels of erythropoietin are 0 to 19 mU/ml (milliunits per millilitre). Elevated levels can be seen in polycythaemia rubra vera. Lower than normal values are seen in chronic renal failure.Recombinant erythopoeitin is now being used therapeutically in patients. Acronym: EPO (27 Sep 1997) |
| haematoporphyria | An obsolete term for any disorder of porphyrin metabolism, regardless of the cause. Origin: haemato-+ G. Porphyra, purple (05 Mar 2000) |
| haematoporphyrin | <protein> A type of artificial porphyrin which forms when sulphuric acid is added to haemoglobin in vitro. It has the chemical formula of C34H38N4O6 and is not found naturally. (09 Oct 1997) |