| genes, rag-1 | Genes involved in activating the enzyme vdj recombinase. Rag-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusively in maturing lymphocytes. (12 Dec 1998) |
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| genes, ras | Family of retrovirus-associated DNA sequences (ras) originally isolated from harvey (h-ras, ha-ras, rash) and kirsten (k-ras, ki-ras, rask) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both h-ras and k-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related n-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein. (12 Dec 1998) |
| genes, recessive | Genes that are reflected in the phenotype only in the homozygous state. (12 Dec 1998) |
| genes, regulator | Genes which regulate or circumscribe the activity of other genes; specifically, genes which code for proteins (repressors or activators) which regulate the genetic transcription of the structural genes and/or regulatory genes. (12 Dec 1998) |
| genes, reporter | Genes whose expression is easily detectable and therefore used to study promoter activity at many positions in a target genome. In recombinant DNA technology, these genes may be attached to a promoter region of interest. (12 Dec 1998) |
| genes, retinoblastoma | Tumour suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kD to 115 kD. One copy of the wild-type rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma. (12 Dec 1998) |
| genes, rev | DNA sequences that form the coding region for a protein that regulates the expression of the viral structural and regulatory proteins in human immunodeficiency virus (HIV). Rev is short for regulator of virion. (12 Dec 1998) |
| genes, src | Retrovirus-associated DNA sequences (src) originally isolated from the rous sarcoma virus (rsv). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20. (12 Dec 1998) |
| genes, structural | Genes that code for proteins required for the enzymatic and structural functions of cells. They include developmental and differentiated genes. (12 Dec 1998) |
| genes, structural, bacterial | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of bacterial cells. (12 Dec 1998) |
| genes, structural, fungal | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of fungal cells. (12 Dec 1998) |
| genes, structural, helminth | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of helminthic cells. (12 Dec 1998) |
| genes, structural, insect | DNA sequences that code for RNA and for proteins required for the enzymatic and structural function of insect cells. (12 Dec 1998) |
| genes, structural, neoplasm | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of neoplastic cells. (12 Dec 1998) |
| genes, structural, plant | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of plant cells. (12 Dec 1998) |
Synonyms : BRCA2 Genes, Gene, BRCA2
Synonyms : Cell Cycle Gene, cdc Gene
Synonyms : DCC Gene, DCC Genes, Gene, DCC
Synonyms : Developmental Gene, Gene, Developmental
Synonyms : Conditions, Dominant Genetic, Dominant Genetic Conditions, Genetic Conditions, Dominant, Condition, Dominant Genetic, Dominant Gene, Dominant Genes, Dominant Genetic Condition, Gene, Dominant, Genetic Condition, Dominant
| gene transfer |
The insertion of genetic material into a cell.
Ãâó: www.stjude.org/glossary
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| gene therapy |
Treatment that alters a gene. In studies of gene therapy for cancer, researchers are trying to improve the body's natural ability to fight the disease or to make the cancer cells more sensitive to other kinds of therapy.
Ãâó: www.stjude.org/glossary
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| general anesthesia |
Drugs that cause loss of feeling or awareness and put the person to sleep.
Ãâó: www.stjude.org/glossary
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| generic |
Official nonbrand names by which medicines are known. Generic names usually refer to the chemical name of the drug.
Ãâó: www.stjude.org/glossary
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| gene flow |
A mechanism for evolutionary change resulting from the movement of genes from one population to another. Gene flow introduces new genes into a population and also acts to make populations more similar genetically to one another.
Ãâó: highered.mcgraw-hill.com/sites/0767430220/student_...
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