| corticosteroid-binding g. |
transcortin.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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|---|---|
| corticosterone 18-monooxygenase |
[EC 1.14.15.5] an enzyme of the oxidoreductase class that catalyzes hydroxylation of corticosteroids at the 18 position followed by oxidation of the 18-hydroxy intermediates, steps in the biosynthesis of aldosterone. The two reactions are sometimes considered separately as I (hydroxylation) and II (oxidation); defects in each reaction have been described and called corticosterone methyl oxidase deficiency, types I and II. The enzyme may be an activity of steroid 11β-monooxygenase (q.v.)
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| corticosterone methyl oxidase |
corticosterone 18-monooxygenase.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| corticosterone methyl oxidase deficiency |
a disorder of steroidogenesis in which deficiency of a corticosterone 18-monooxygenase impairs the biosynthesis of aldosterone and causes salt wasting. It occurs as two types: type I, in which decreased hydroxylation of corticosterone results in corticosterone and deoxycorticosterone accumulation, and type II, in which decreased oxidation of the 18-hydroxy intermediate results in elevated levels of this compound and corticosterone. Called also 18-hydroxylase deficiency.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| corticostriatal-spinal d. |
Creutzfeldt-Jakob disease.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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