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alpha-santonin-1,2-reductase <enzyme> From pseudomonas cichorii s.; catalyses the reduction of the 1,2-double bond of santonin; NADH or NADPH dependent
Registry number: EC 1.3.1.-
Synonym: santonin 1,2-reductase
(26 Jun 1999)
alpha-sarcin A fungal toxin that acts on the large subunit of rRNA and inactivates the ribosome.
(05 Mar 2000)
alpha-streptococci Streptococci that form a green variety of reduced haemoglobin in the area of the colony on a blood agar medium.
(05 Mar 2000)
alpha substance A filamentous plasmatic material, beaded with granules, demonstrable by means of vital staining in the immature red blood cells.
Synonym: alpha substance, filar mass, filar substance, substantia reticularis, substantia reticulofilamentosa.
Synonym: reticular formation.
(05 Mar 2000)
Alpha tests A set of paper and pencil-administered mental tests first used in the United States Army in 1917-1918 to determine the mental ability of literate recruits; the set includes 8 different types of tests: i.e., directions, arithmetical problems, practical judgement, synonyms and antonyms, disarrayed sentences, number series completions, analogies, and information; they are designed especially for testing large groups of individuals simultaneously, and for rapid machine scoring; distinguished from the Army Beta tests, a complementary set for administration to recruits who could not read or write English, in which the instructions are given in signs and the test material is pictorial.
See: Beta tests.
Synonym: Army Alpha tests.
(05 Mar 2000)
alpha thalassaemia <haematology> A condition characterised by the reduced synthesis of the alpha chain of haemoglobin due to abnormality in one of two or more genes that code for the synthesis of alpha-globin chains. The severity of this condition can vary from mild anaemia to death, depending on the number of genes deleted.
Heterozygous state: severe type, thalassaemia minor with 5 to 15% of Hb Barts at birth, only traces of Hb Barts in adult; mild type, 1 to 2% of Hb Barts at birth, not detectable in adult.
Homozygous state: severe type, erythroblastosis foetalis and foetal death, only Hb Barts and Hb H present; mild type not clinically defined.
See: haemoglobin H.
(05 Mar 2000)
alpha-tocopherol <chemical> A light yellow, viscous, odourless, oily liquid that deteriorates on exposure to light, is obtained from wheat germ oil or by synthesis, biologically exhibits the most vitamin E activity of the alpha-tocopherol's, and is an antioxidant retarding rancidity by interfering with the autoxidation of fats.
Prepared from natural phytol, it is called 2-ambo-alpha-tocopherol; from synthetic phytol, all-rac-alpha-tocopherol or synt-alpha-tocopherol; also available are d-alpha-tocopheryl acetate, dl-alpha-tocopheryl acetate, d-alpha-tocopheryl acid succinate, and d-alpha-tocopheryl acetate concentrate. One of several forms of vitamin E.
Chemical name: 2,5,7,8-tetramethyl-2-(4',8',12'-trimeth yltridecyl)-6-chromanol; 5,7,8-trimethyltocol
Synonym: vitamin E.
(14 Aug 2000)
alpha-tubulin acetylase <enzyme> From chlamydomonas flagella; catalyses the acetylation of alpha-tubulin-l-lysine in the presence of acetyl-CoA to yield CoA and alpha-tubulin n(epsilon)-acetyl-l-lysine
Registry number: EC 2.3.1.108
Synonym: alpha-tubulin acetyltransferase
(26 Jun 1999)
alpha units Cytoplasmic glycogen granules arranged in rosettes.
(05 Mar 2000)
alpha wave Brain waves in the encephalogram which have a frequency of 8 to 13 per second. They are typical of the normal person awake and in a quiet resting state, and occur principally in the occipital region.
(12 Dec 1998)
androstenedione 17-alpha-oxidoreductase <enzyme> Forms epitestosterone; was mapped to testosterone dehydrogenases (85-93); index medicus see under 17-hydroxysteroid dehydrogenases (85-90)
Registry number: EC 1.1.1.-
Synonym: steroid 17alpha oxidoreductase, androstenedione 17-oxidoreductase
(26 Jun 1999)
aryl-alpha-mannosidase <enzyme> Act on p-nitrophenyl-alpha-d-mannopyranoside
Registry number: EC 3.2.1.-
Synonym: aryl-alpha-mannosidase a, aryl-alpha-mannosidase b
(26 Jun 1999)
aspartate-alpha-decarboxylase <enzyme> Forms beta-alanine
Registry number: EC 4.1.1.11
Synonym: aspartate 1-decarboxylase
(26 Jun 1999)
beta-D-galactoside alpha 2-6-sialyltransferase <enzyme> Catalyses the reaction of cmp-n-acetylneuraminate and galactosylglycoprotein to yield cmp and n-acetylneuraminylgalactosylglycoprotein; cd75 and cd75w antigen were removed as sys - it is not equivalent to the enzyme.
Registry number: EC 2.4.99.1
Synonym: cmp-n-acetylneuraminate-d-galactosyl-glycoprotein n-acetylneurainyltransferase, cmp-n-acetylneuraminate-beta-galactoside alpha-2,6-sialyltransferase, beta-galactosyl(1-4)n-acetylglucosaminide alpha(2-6)-sialyltransferase, gal-glcnac(2-6)-sialyltransferase, cmp-n-acetylneuraminic acid-lactose sialytransferase, cmp-acetylneuraminate galactoside (alpha 2-6)-sialyltransferase, cmp-n-acetylneuraminate-galactosylglycoprotein sialyltransferase, alpha 2-6-sialyltransferase, cmp-sialic acid-n-acetyllactosaminide alpha (2-6)-sialyltransferase, cmp-neuac-galactoside (alpha 2-6)-sialyltransferase, gal-1-4-glcnac alpha(2-6)-sialyltransferase, siat-1, beta-galctoside alpha2,6-sialyltransferase
(26 Jun 1999)
beta-galactoside alpha-2,3-sialyltransferase <enzyme> Transfers sialic acid residue from cmp-n-acetylneuraminic acid to an acceptor galactoside
Registry number: EC 2.4.99.4
Synonym: alpha 2-3-sialyltransferase, cmp-neuac-galactoside (alpha 2-3)-sialyltransferase, cmp-angs-transferase, cmp n-acetylneuraminate-beta-galactoside alpha-2,3-sialyltransferase, cmpsialic acid beta-galactosyl-1-3-n-acetylgalactosaminide alpha 2-3-sialyltransferase, beta-d-galactoside 3-alpha-sialyltransferase, cmp-acetylneuraminate-galactoside (alpha 2-3)-sialyltransferase, asialofetuin sialyltransferase, gal beta1,3galnac alpha2,3-sialyltransferase, cmp-neu5ac-gal beta1-3galnac alpha-2,3-sialyltransferase, cmp-neu5ac-gal1-3galnac alpha-2,3-sialyltransferase, alpha-2,3-st(o)
(26 Jun 1999)
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