| steroid 11-alpha-hydroxylase | <enzyme> Converts 11-deoxycortisol to 11-alpha cortisol (the 11-alpha isomer of hydrocortisone) Registry number: EC 1.14.99.- (26 Jun 1999) |
|---|---|
| steroid 14-alpha-hydroxylase | <enzyme> From induced vegetative cell cultures of mucor piriformis; hydroxylates progesterone to 14-alpha-hydroxyprogesterone in the presence of NADPH and oxygen Registry number: EC 1.14.13.- Synonym: progesterone 14-alpha-hydroxylase (26 Jun 1999) |
| steroid 17 alpha-monooxygenase | <enzyme> A steroid hydroxylase system found in the microsomal membrane of the steroid-hormone producing tissues. It catalyses the 17-hydroxylation of steroids, such as progesterone or pregnenolone in the presence of NADPH and molecular oxygen. This is an important step in the biosynthesis of steroid hormones. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating) Registry number: EC 1.14.99.9 (12 Dec 1998) |
| steroid 7 alpha-hydroxylase | <enzyme> Testosterone and androstenedione incubated with microsomes from rat testes produced 7alpha-hydroxytestosterone and 7alpha-hydroxyandrostenedione Registry number: EC 1.14.99.- Synonym: testicular 7 alpha-hydroxylase, 7 alpha-hydroxylase, microsomal 7alpha-hydroxylase, andiostenedione 7 alpha-hydroxylase, sterol 7 alpha-hydroxylase, cytochrome p-450iia1, cytochrome p450iia1 (26 Jun 1999) |
| steroid 9 alpha monooxygenase | <enzyme> Consists of an electron transport chain of NADH-dependent flavoprotein reductase and 2 iron-sulfur proteins; from nocardia Registry number: EC 1.14.99.- Synonym: steroid 9 alpha-hydroxylase (26 Jun 1999) |
| steroid alpha-ketol oxidase | <enzyme> In conjunction with corticosteroid side-chain-isomerase (EC 5.3.1.21) converts desoxycorticosterone to a 20-oxo-21-oic acid (pregnenoic acid) Registry number: EC 1.2.1.- (26 Jun 1999) |
| N-nitrosopyrrolidine alpha-hydroxylase | <enzyme> A variety of cytochrome p-450 isoenzymes involved in rabbit liver microsomal activity Registry number: EC 1.14.13.- Synonym: npa-hydroxylase (26 Jun 1999) |
| sucrose alpha-d-glucohydrolase | <enzyme> An enzyme hydrolyzing sucrose and maltose; in a complex with isomaltase; hence, hydrolyzes both sucrose and isomaltose; found in the intestinal mucosa; a deficiency of this enzyme results in defective digestion of sucrose and linear a1,4-glucans. Synonym: sucrase. (05 Mar 2000) |
| d(-)-alpha-aminobenzylpenicillin | <drug> Penicillin derivative with broad spectrum activity, ampicillin resistance is often used as a marker for plasmid transfer in genetic engineering (for example pBR322 is ampicillin resistant). (13 Nov 1997) |
| deficiency, alpha-1 antitrypsin | An inherited disease with little or no production of an important protein, alpha-1 antitrypsin. The lack of this protein leads to damage of various organs, mainly the lung and liver. The disease may become apparent at a very early age or in adulthood, as shortness of breath or liver-related symptoms (jaundice, fatigue, fluid in the abdomen, mental changes, or gastrointestinal bleeding). There are several options for treatment of the lung disease, including replacement of the missing protein. Treatment of the liver disease is a well-timed liver transplant (12 Dec 1998) |
| delta-(alpha-aminoadipyl)cysteinylvalinedisulfide reductase | <enzyme> Broad range disulfide reductase from streptomyces clavuligerus; requires NADPH; involved in the production of beta-lactam antibiotic such as penicillins and cephalosporins Registry number: EC 1.6.4.- Synonym: bis-acv reductase, delta-(-l-alpha-aminoadipyl)-l-cysteinyl-d-valine disulfide reductase, acv disulfide reductase (26 Jun 1999) |
| dextrin 6-alpha-d-glucosidase | <enzyme> Catalyses endohydrolysis of 1,6-alpha-d-glucoside linkages at points of branching in chains of 1,4-linked alpha-d-glucose residues Registry number: EC 3.2.1.33 (26 Jun 1999) |
| diadenosine 5,5'''-P(1),P(4)-tetraphosphate alpha,beta-phosphorylase | <enzyme> Ap4a + inorganic po4 forms ATP + ADP Registry number: EC 2.7.7.53 Synonym: ap4a phosphorylase, ATP adenylyltransferase (26 Jun 1999) |
| dihydrostreptomycin-6-phosphate 3' alpha-kinase | <enzyme> Catalyses the phosphorylation of dihydrostreptomycin 6-phosphate in the 3'-position in the presence of ATP Registry number: EC 2.7.1.88 Synonym: dihydrostreptomycin-6-p 3' alpha-kinase (26 Jun 1999) |
| dolichyl-phosphate alpha-N-acetylglucosaminyltransferase | <enzyme> Combined with EC 2.4.1.141 forms chitobiosylpyrophosphoryldolichol synthase Registry number: EC 2.4.1.153 Synonym: dpagtransferase (26 Jun 1999) |