| IHR | intrahepatic resistance; intrinsic heart rate |
|---|---|
| IPR | insulin production rate; intraparenchymal resistance; ipratropium |
| IRI | immunoreactive insulin; insulin resistance index |
| MDR | median duration of response; medical device reporting; minimum daily requirement; multidrug resistan... |
| MHR | major histocompatibility region; malignant hyperthermia resistance; maternal heart rate; maximal hea... |
| oncogene proteins, viral | Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and often protein kinase activities. (12 Dec 1998) |
|---|---|
| encephalitis, viral | Inflammation of the brain caused by viruses. When this is caused by encephalitis viruses, a group of arboviruses, it is referred to as epidemic encephalitis (encephalitis, epidemic). Other viruses, including some herpes viruses, also cause viral encephalitis. (12 Dec 1998) |
| equine viral arteritis | A highly contagious viral disease caused by equine arteritis virus, member of the family Togaviridae, and characterised by a high fever and respiratory and digestive tract signs; the essential lesions involve smaller arteries, with necrosis which may be followed by thrombosis, infarction, haemorrhages, and oedema; abortion is a common result. Synonym: epizootic cellulitis, equine typhoid. (05 Mar 2000) |
| eye infections, viral | Infections of the eye caused by minute intracellular agents. These infections may lead to severe inflammation in various parts of the eye - conjunctiva, iris, eyelids, etc. Several viruses have been identified as the causative agents. Among these are herpes virus, adenovirus, poxvirus, and myxovirus. (12 Dec 1998) |
| feline viral rhinotracheitis | An acute upper respiratory tract infection of cats caused by the feline rhinotracheitis virus; it is frequently fatal in kittens but mild in adults, who sometimes become convalescent carriers of the virus. (05 Mar 2000) |
| abnormalities, drug-induced | Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment. (12 Dec 1998) |
| activity, drug | A measure of the physiological response a drug produces in the body. A less active drug produces less response (and visa versa). (12 Dec 1998) |
| addictive drug | Any drug that creates a certain degree of euphoria and has a strong potential for addiction. (05 Mar 2000) |
| adverse drug reaction reporting systems | Systems developed for collecting reports from government agencies, manufacturers, hospitals, physicians, and other sources on adverse drug reactions. (12 Dec 1998) |
| akathisia, drug-induced | Motor restlessness with sensations of quivering and an urge to move about constantly resulting from the use of certain drugs, such as neuroleptic drugs, which affect the extrapyramidal region of the brain. This differs from dyskinesia, drug-induced in that long-term antipsychotic drug exposure is significantly correlated with the increased prevalence of akathisia while there is no such correlation with dyskinesia. The primary observable distinction between tardive akathisia and dyskinesia appears to be in the repetitive, stereotypy of the dyskinesic movements (lip smacking, for example), while akathisia is associated with anxiety, restlessness, and agitation (psychomotor agitation). (12 Dec 1998) |
| antineoplastic drug | A drug that stops or slows the maturation and spread of tumour cells (benign or malignant). (09 Oct 1997) |
| maintenance drug therapy | In chemotherapy, systematic dosage at a level that maintains protection against exacerbation. (05 Mar 2000) |
| rational drug design | <pharmacology> Modeling the molecular structure of the target of a drug, for example, an antigen, and then designing a drug that will attack it. (17 Dec 1997) |
| receptors, drug | Proteins that bind specific drugs with high affinity and trigger intracellular changes influencing the behaviour of cells. Drug receptors are generally thought to be receptors for some endogenous substance not otherwise specified. (12 Dec 1998) |
| recreational drug | A controlled substance taken for non-medical purposes. Street drugs comprise various amphetamines, anaesthetics, barbiturates, opiates, and psychoactive drugs, and many are derived from natural sources (e.g., the plants Papaver somniferum, Cannibis sativa, Amanita pantherina, Lophophora williamsii). Slang names include acid (lysergic acid diethylamide), angel dust (phencyclidine), coke (cocaine), downers (barbiturates), grass (marijuana), hash (concentrated tetrahydrocannibinol), magic mushrooms (psilocybin), mescaline (peyote), speed (amphetamines). During the 1980s, a new class of "designer drugs" arose, mostly analogs of psychoactive substances intended to escape regulation under the Controlled Substances Act. Also, crack cocaine, a potent, smokable form of cocaine, emerged as a major public health problem. In the U.S. Illicit use of drugs such as cocaine, marijuana, and heroin historically has occurred in cycles. Synonym: recreational drug. (05 Mar 2000) |