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DNA writhing <molecular biology> Coiling of a double-stranded DNA molecule in such a way that it crosses its own (longitudinal) axis.
(09 Oct 1997)
double-stranded complimentary DNA <molecular biology> A duplex DNA molecule copied from a copy DNA template.
(09 Oct 1997)
dyad symmetry of DNA <molecular biology> Two areas of a DNA molecule whose base pair sequences are repeats of each other, inverted relative to each other, or are palindromes.
(09 Oct 1997)
O(2)-methylthymine-DNA glycosidase <enzyme> Repairs o(2)-methylthymidine residues in DNA
Registry number: EC 3.2.2.-
Synonym: mth-DNA glycosidase
(26 Jun 1999)
O(4)-methylthymine-DNA methyltransferase <enzyme> Repairs o(4)-methylthymidine residues in DNA
Registry number: EC 2.1.1.-
Synonym: mth-DNA methyltransferase
(26 Jun 1999)
o(6)-methylguanine-DNA methyltransferase <enzyme> An enzyme that transfers methyl groups from o(6)-methylguanine, and other methylated moities of DNA, to a cysteine residue in itself, thus repairing alkylated DNA in a single-step reaction.
Chemical name: DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase
Registry number: EC 2.1.1.63
(12 Dec 1998)
technology, recombinant DNA A series of procedures used to join together (recombine) DNA segments. A recombinant DNA molecule is constructed (recombined) from segments from 2 or more different DNA molecules. Under certain conditions, a recombinant DNA molecule can enter a cell and replicate there, autonomously (on its own) or after it has become integrated into a chromosome.
(12 Dec 1998)
Tet DNA polymerase <enzyme> From thermus thermophilus; thermostable, used as a replacement for taq polymerase in DNA sequencing
Registry number: EC 2.7.7.-
Synonym: DNA polymerase tet
(26 Jun 1999)
transfer DNA <molecular biology> The transforming region of DNA in the Ti plasmid of agrobacterium tumefaciens.
Acronym: t-DNA
(04 Jul 1999)
triple DNA <molecular biology> A variation of DNA, in which there is a third strand of nucleotides binding to the first two by specific base pairing.
(14 Nov 1997)
exogenous DNA <molecular biology> DNA originating outside an organism.
(09 Oct 1997)
junk DNA That portion of DNA which is not transcribed and expressed, comprising about 90% of the 3 billion base pairs of the human genome; its function is not known.
(05 Mar 2000)
extrachromosomal DNA DNA that occurs naturally outside of the nucleus (e.g., mitochondrial DNA).
(05 Mar 2000)
UlTma DNA polymerase <enzyme> A thermostable DNA polymerase with putative proofreading activity
Registry number: EC 2.7.7.-
(26 Jun 1999)
Z-DNA <molecular biology> A form of DNA, or a region of DNA, in which the helix is flipped into a lefthanded helix, characterised by alternating purines and pyrimidines.
This region is thought to be the target of a DNA-binding protein.
(20 Jun 2000)
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