| atopic dermatitis | <dermatology> A type of immune-mediated (allergic) inflammatory skin disorder that results in a itchy rash. See: atopic eczema. (27 Sep 1997) |
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| atopic eczema | <dermatology> An inflammatory condition of the skin that includes redness, itching and oosing vesicular lesions which become scaly, crusted or hardened. Causes include hypersensitivity to chemicals, metals (nickel) or plants (for example Poison Ivy) or chronic irritation detergents or soaps. Anxiety, stress and depression may all play a role in the exacerbation of eczema. Those with atopic eczema may be discovered to have an increased eosinophil count in their blood. Treatment often includes mild anti-pruritic lotions and corticosteroid creams. Careful avoidance of any irritating substances will be mandatory. (27 Sep 1997) |
| atopic keratoconjunctivitis | A chronic papillary inflammation, of the conjunctiva showing Trantas dots in a patient with a history of hypersensitivity. (05 Mar 2000) |
| atopic reagin | One of the IgE class of antibody's first demonstrated by Prausnitz and Kustner by passive transfer to the skin. See: homocytotropic antibody. Synonym: atopic reagin. (05 Mar 2000) |
| atopognosia | Atopognosis Sensory inattention; inability to locate a sensation properly. Usually caused by a contralateral parietal lobe lesion. Origin: G. A-priv. + topos, place, + gnosis, knowledge (05 Mar 2000) |
| atopy | <immunology> An allergic reaction with strong family tendencies. (09 Oct 1997) |
| atovaquone | <drug> A medication for mild to moderate cases of PCP as well as for salvage treatment of toxoplasmosis. A new, more absorbable liquid formulation has entered the market. Atovaquone should be used with caution along with rifampin and fluconazole since these drugs can lower atovaquone blood levels. (09 Oct 1997) |
| atoxic | <pharmacology> Not poisonous, not due to a poison. Origin: Gr. Toxikon = poison (16 Dec 1997) |
| ATP | <biochemistry> A nucleotide present in all living cells which serves as an energy source for many metabolic processes and is required for ribonucleic acid synthesis. (06 May 1997) |
| ATP citrate (pro-3S)-lyase | <enzyme> An enzyme that, in the presence of ATP and CoA, catalyses the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and orthophosphate. This reaction represents an important step in fatty acid biosynthesis. Chemical name: ATP:citrate oxaloacetate-lyase ((pro-S)-CH2COO(-)--acetyl-CoA) (ATP-dephosphorylating) Registry number: EC 4.1.3.8 Synonym: citrate cleavage enzyme. (12 Dec 1998) |
| ATP citrate lyase | ATP citrate (pro-3S)-lyase |
| ATP cobalamin adenoxyltransferase | <enzyme> An enzyme that catalyses the reaction of ATP, water, and cobalamin to form orthophosphate, pyrophosphate, and adenoxylcobalamin. Adenosylcobalamin is required by methylmalonyl-CoA mutase. A deficiency of ATP cobalamin adenosyltransferase will lead to methylmalonic acidemia. (05 Mar 2000) |
| ATP dependent 26S protease | <enzyme> Degrades proteins conjugated to ubiquitin; composed of cf-1,cf-2, and cf-3; cf-2 (also known as 240-kD proteasome inhibitor) is identical to aminolevulinic acid dehydratase Registry number: EC 3.4.99.- Synonym: 26s protease, 26 s proteasome complex, 26s proteasome (26 Jun 1999) |
| ATP phosphoribosyltransferase | <enzyme> An enzyme that catalyses the first step of the pathway for histidine biosynthesis in salmonella typhimurium. ATP reacts reversibly with 5-phosphoribosyl-1-pyrophosphate to yield n-1-(5'-phosphoribosyl)-ATP and pyrophosphate. Chemical name: 1-(5-Phospho-D-ribosyl)-ATP:pyrophosphate phospho-alpha-D- ribosyltransferase Registry number: EC 2.4.2.17 (12 Dec 1998) |
| ATP sulfurylase | <enzyme> An enzyme that catalyses the activation of sulfate ions by ATP to form adenosine-5'-phosphosulfate and pyrophosphate. This reaction constitutes the first enzymatic step in sulfate utilization following the uptake of sulfate. Chemical name: ATP:sulfate adenylyltransferase Registry number: EC 2.7.7.4 (12 Dec 1998) |