| GPEBP | granulocyte colony-stimulating factor promoter element binding protein |
|---|---|
| GRB | growth factor receptor-binding protein |
| HBP | heartbeat period; hepatic binding protein; high blood pressure; hospital-based practice |
| HDLBP | high-density lipoprotein binding protein |
| ICBP | intracellular binding protein |
| globular protein | <molecular biology> Any protein that adopts a compact morphology is termed globular. Generally applied to proteins in free solution that have a more-or-less spherical shape, but may also be used for compact folded proteins within membranes. (14 Oct 1997) |
|---|---|
| cdc28 protein kinase | <enzyme> A protein kinase encoded by the saccharomyces cerevisiae cdc28 gene and required for progression from the g1 to the s phase in the cell cycle. It is a complex of approximately 160 kD containing a substrate called p40. Registry number: EC 2.7.1.- (12 Dec 1998) |
| cdc2+-CDC28-related protein kinase | <enzyme> From rice; key enzyme for cell cycle regulation in eukaryocytes; belongs to serine-threonine kinase subfamily Registry number: EC 2.7.10.- Synonym: cdc2-cdc28-pk, cdc2-cdc28-rp kinase (26 Jun 1999) |
| CDC5 protein kinase | <enzyme> Phosphorylates the residues that play a crucial role in mitotic function; genes msd2 and cdc5 are identical; 705 aa residues, mw 81 kD genbank m84220 Registry number: EC 2.7.1.- Synonym: cdc5 gene product (26 Jun 1999) |
| CDC7 protein kinase | <enzyme> From saccharomyces cerevisiae; amino acid sequence has been determined; human cdc7 (hucdc7) is genbank ab003698; xenopus cdc7 (xecdc7) is genbank ab003699 Registry number: EC 2.7.1.- Synonym: cdc7 gene product, hucdc7, xecdc7 (26 Jun 1999) |
| Cek4 receptor protein-tyrosine kinase | <enzyme> Isolated from mouse and chicken. Registry number: EC 2.7.1.- Synonym: cek4 protein, cek4 eph receptor, eph receptor cek4 (26 Jun 1999) |
| cell-free protein synthesis | <technique> An in vitro method to make proteins, using amino acids, the mRNA corresponding to the protein to be made, and a cell-free extract (the contents of a cell after removal of the cell wall and/or outer cell membranes) for other needed components and enzymes. (26 Mar 1998) |
| PCTAIRE-2 protein kinase | <enzyme> Member of a subfamily of cdc-2-related kinases preferentially expressed in post-mitotic cells; amino acid sequence has been determined Registry number: EC 2.7.10.- (26 Jun 1999) |
| glucose related protein | <protein> One of the stress related proteins: identical to endoplasmin. (18 Nov 1997) |
| rep protein | <protein> A protein that triggers a plasmid's replication. An acronym for Repetitive Extragenic Palindromicprotein, this protein is an enzyme produced by a mutant strain of E. Coli that unwinds the DNA helix. (09 Oct 1997) |
| repressor protein | <molecular biology> A protein that binds to an operator of a gene preventing the transcription of the gene. The binding affinity of repressors for the operator may be affected by other molecules. Inducers bind to repressors and decrease their binding to the operator, while co repressors increase the binding. The paradigm of repressor proteins is the lactose repressor protein that acts on the lac operon and for which the inducers are _ galactosides such as lactose, it is a polypeptide of 360 amino acids that is active as a tetramer. Other examples are the lambda repressor protein of lambda bacteriophage that prevents the transcription of the genes required for the lytic cycle leading to lysogeny and the cro protein, also of lambda, which represses the transcription of the lambda repressor protein establishing the lytic cycle. Both of these are active as dimers and have a common structural feature the helix turn helix motif that is thought to bind to DNA with the helices fitting into adjacent major grooves. (18 Nov 1997) |
| VLA protein | <protein> VLA 1 and VLA 2 were originally defined as antigens appearing on the surfaces of T lymphocytes 2-4 weeks after in vitro activation, they are now know to be part of the _ integrin family. Additional members of the subset are now known (VLA 3, VLA 4, VLA 5 and VLA 6), the _ subunits all being identical. Some of the VLA proteins are receptors for collagen, laminin or fibronectin and many are now known to be expressed on cells other than leucocytes. (18 Nov 1997) |
| pelle-like protein kinase | <enzyme> Mplk - mouse pelle-like kinase; mammalian homolog of drosophila pelle protein; expression is developmentally regulated and is greatest in liver; genbank l08476 Registry number: EC 2.7.10.- Synonym: mplk (protein) (26 Jun 1999) |
| ceramide-activated protein kinase | <enzyme> Mw 97 kD; stimulation of kinase takes place during sphingomyelin pathway; has membrane-bound activity capable of phosphorylating a peptide derived from the sequence surrounding thr(699) of the epidermal growth factor receptor; has role in signal transduction for tumour necrosis factor Registry number: EC 2.7.10.- Synonym: cap kinase (26 Jun 1999) |
| ceramide-activated protein phosphatase | <enzyme> Belongs to the heterotrimeric subfamily of the pp2a group of serine-threonine protein phosphatases; involved in ceramide-mediated signal transduction; inhibited by okadaic acid Registry number: EC 3.1.3.- Synonym: ceramide-stimulated phosphatase, capp (enzyme) (26 Jun 1999) |