| tumour specific antigen | <immunology, oncology> Antigen on tumour cells detected by cell-mediated immunity. For virus transformed cells TSTA (unlike T antigen) is found to differ for different individual tumours induced by the same virus. May consist of fragments of T antigens exposed at the cell surface. (18 Nov 1997) |
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| tumour-specific transplantation antigens | Surface antigen's of DNA tumour virus-transformed cells, which elicit an immune rejection of the virus-free cells when transplanted into an animal that has been immunised against the specific cell-transforming virus. (05 Mar 2000) |
| tumour stage | <oncology> The extent of the spread of a malignant neoplasm from its site of origin. See: TNM staging. (05 Mar 2000) |
| tumour stem cell assay | <investigation> A cytologic technique for measuring the functional capacity of tumour stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agent. (12 Dec 1998) |
| tumour stem cells | <cell biology> Colony-forming cells which give rise to neoplasms. (12 Dec 1998) |
| tumour suppressor | <molecular biology, oncology> A gene that encodes a product that normally negatively regulates the cell cycle and that must be mutated or otherwise inactivated before a cell can proceed to rapid division. Examples: p53, RB retinoblastoma), WT 1 (Wilm's tumour), DCC (deleted in colonic carcinoma), NF 1 (neurofibrosarcoma) and APC adenomatous polyposis coli). (18 Nov 1997) |
| tumour virus | <oncology, virology> Virus capable of inducing tumours. (18 Nov 1997) |
| tumour viruses, murine | Species of mammalian type c retroviruses (retroviruses type c, mammalian) that cause solid tumours or leukaemias in mice. (12 Dec 1998) |
| tumour virus infections | Infections produced by oncogenic viruses. The infections caused by DNA viruses are less numerous but more diverse than those caused by the RNA oncogenic viruses. (12 Dec 1998) |
| turban tumour | Cylindroma of the scalp which, when overgrown, may resemble a turban. (05 Mar 2000) |
| Ewing's tumour | A malignant primary bone tumour that arises most commonly in the first three decades of life. It is highly malignant (prone to spread) and often requires treatment with some combination of radiation therapy and chemotherapy. (27 Sep 1997) |
| faecal tumour | An accumulation of inspissated faeces in the colon or rectum giving the appearance of an abdominal tumour. Synonym: faecal tumour, fecaloma, scatoma, stercoroma. Origin: copro-+ G. -oma, tumour (05 Mar 2000) |
| yaba monkey tumour virus | The type species of yatapoxvirus, a tumour-producing DNA virus discovered in monkeys in yaba, nigeria. It has been found to produce histiocytomas in monkeys and humans. (12 Dec 1998) |
| Yaba tumour | <oncology, virology> A poxvirus-induced neoplasm of African monkeys caused by the Yaba monkey virus, a member of the family Poxviridae. It is associated with tumour-like growths occur chiefly on the head and limbs. The tumours are benign and the natural disease has been reported only in Africa in monkeys kept outdoors. (05 Mar 2000) |
| yolk sac tumour | An unusual and aggressive tumour of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumour found in children. It is characterised by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (schiller-duval body). The tumour is rarely bilateral. Before the use of combination chemotherapy, the tumour was almost invariably fatal. (12 Dec 1998) |