| interference reflection microscopy | <procedure> An optical technique for detecting the topography of the side of a cell in contact with a planar substrate and for providing information on the separation of the plasmalemma from the substrate. Interference between the reflections from the substrate medium interface and the reflections from the plasmalemma medium interface generate the image. (18 Nov 1997) |
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| interferometer | <radiobiology> Device which measures changes in a medium by looking at effects on the interference of two waves which are passed through that medium. See: interferometry, laser interferometer, optical inteferometer, Fabry-Perot interferometer, microwave interferometer. (09 Oct 1997) |
| interferometry | <radiobiology> Method of gathering information about a medium by using an interferometer or similar technique. Optical - Uses light as the wave to be interfered. Microwave - Uses microwaves instead. Microwave interferometry is especially useful in plasma physics for measuring plasma densities. (09 Oct 1997) |
| interferon | <cytokine> A family of glycoproteins derived from human cells which normally has a role in fighting viral infections by preventing virus multiplication in cells. They are secreted by vertebrate cells in response to a wide variety of inducers and confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. Interferon-alpha is made by leucocytes and interferon-gamma by fibroblasts after viral infection. Interferon-alpha and -beta are also called type I interferons, interferon-gamma as Type II interferons, more usually classed as cytokines. Pharmacological action: antineoplastic agent, antiviral agents. (20 Sep 2002) |
| interferon inducers | Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic polymers poly a-u and poly I-c. Viruses, bacteria, and protozoa have been also known to induce interferons. (12 Dec 1998) |
| interferon type I | <chemical> Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens, or allo-antigens. They include alpha- and beta-interferons (interferon-alpha and interferon-beta). Pharmacological action: antineoplastic agent, antiviral agents. (12 Dec 1998) |
| interferon type II | <chemical> The major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon (interferon type I) and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Pharmacological action: antineoplastic agent, antiviral agents. Chemical name: Interferon-gamma (human lymphocyte protein moiety reduced) (12 Dec 1998) |
| interferon-alpha | <cytokine> One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded RNA, or bacterial products. It is the major interferon produced by virus-induced leukocyte cultures and, in addition to its pronounced antiviral activity, causes activation of NK cells. It is used experimentally in the treatment of hairy-cell leukaemia. A number of different subtypes exist that are elaborated by leukocytes in response to viral infection or stimulation with double-stranded RNA; IFN-alpha-2A and -2B are protein products made by recombinant DNA techniques and are used as antineoplastic agents. See: interferon-alpha 2a, interferon-alpha 2b Synonym: leukocyte interferon. Pharmacological action: antineoplastic agent, antiviral agent. (20 Sep 2002) |
| interferon-alpha 2a | <cytokine> Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. Pharmacological action: antineoplastic agent, antiviral agents. Chemical name: Interferon-alphaA (human leukocyte protein moiety reduced) (12 Dec 1998) |
| interferon-alpha 2b | <chemical> Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. Pharmacological action: antineoplastic agent, antiviral agents. (12 Dec 1998) |
| interferon-b2 | <cytokine> A cytokine that stimulates the growth and differentiation of human B-cells and is also a growth factor for hybridomas and plasmacytomas. It is produced by many different cells including T-cells, monocytes, and fibroblasts. A single chain 25 kD cytokine originally described as a pre B-cell growth factor, now known to have effects on a number of other cells including T-cells which are also stimulated to proliferate. An inducer of acute phase proteins and a colony-stimulating factor acting on mouse bone marrow. Acronym: IL-6 (12 Dec 1998) |
| interferon-beta | <cytokine> One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity. Synonym: fibroblast interferon. Pharmacological action: adjuvants, immunologic, antineoplastic agent, antiviral agents. Chemical name: Interferon-alphaB (human leukocyte protein moiety reduced) (12 Dec 1998) |
| interferon-gamma | <cytokine> Interferon elaborated by T lymphocytes in response to either specific antigen or mitogenic stimulation. This type II interferon can be produced by recombinant DNA technology and is similar to the interferon secreted by lymphocytes and has antiviral and antineoplastic activity. Synonym: antigen interferon, immune interferon. Pharmacological action: antineoplastic agent, antiviral agents. (20 Sep 2002) |
| interfibrillary | Between fibrils. (05 Mar 2000) |
| interfibrous | Between fibres. (05 Mar 2000) |
Synonyms : CD122 Antigen, IL-2-15 Receptor-beta, IL-2R BETA, IL-2Rbeta2, Interleukin 2-15 Receptors-beta, Interleukin-2 Receptor beta, Interleukin-2 Receptor beta Chain, Interleukin-2-15 Receptor-beta, Interleukin-Binding Peptide p75, IL 2 15 Receptor beta, IL 2R BETA
Synonyms : IL-21 Receptor alpha Chain, Interleukin-21 Receptor alpha Chain, IL 21 Receptor alpha Chain, Interleukin 21 Receptor alpha Chain, Interleukin 21 Receptor alpha Subunit
Synonyms : Interleukin 23
Synonyms : IL-23 p19, IL-23p19, Interleukin-23 alpha Subunit, Interleukin 23 Subunit p19, Interleukin 23 alpha Subunit, alpha Subunit, Interleukin-23
Synonyms : Eosinophil-Mast Cell Growth-Factor, Hematopoietin-2, Burst Promoting Factor, Erythrocyte, Colony Stimulating Factor, Mast Cell, Colony Stimulating Factor, Multipotential, Eosinophil Mast Cell Growth Factor, Erythrocyte Burst Promoting Factor, Hematopoietin 2
| intermediate |
lying between two extremes in time or space or degree; "going from sitting to standing without intermediate pushes with the hands"; "intermediate stages in a process"; "intermediate stops on the route"; "an intermediate level" intercede: act between parties with a view to reconciling differences; "He interceded in the family dispute"; "He mediated a settlement" a substance formed during a chemical process before the desired product is obtained average: around the middle of a scale of evaluation of physical measures; "an orange of average size"; "intermediate capacity"; "a plane with intermediate range"; "medium bombers"
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| intersex |
hermaphrodite: one having both male and female sexual characteristics and organs; at birth an unambiguous assignment of male or female cannot be made
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| interstice |
a small structural space between tissues or parts of an organ; "the interstices of a network" small opening between things
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| intermediate host |
a host that is used by a parasite in the course of its life cycle
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| intermittence |
the quality of being intermittent; subject to interruption or periodic stopping
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| inter | the trade of planning the layout and furnishings of an architectural interior |
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| inter | decoration consisting of the layout and furnishings of a livable interior |
| inter | a person who specializes in designing architectural interiors and their furnishings |
| inter | the federal department charged with conservation and the development of natural resources |
| inter | the trade of planning the layout and furnishings of an architectural interior |
| inter | the branch of architecture dealing with the selection and organization of furnishings for an architectural interior |
| inter | a person who specializes in designing architectural interiors and their furnishings |
| inter | a door that closes off rooms within a building |
| inter | medium-small shrubby evergreen tree of western North America similar to the coast live oak but occurring chiefly in foothills of mountain ranges removed from the coast |
| inter | a literary genre that presents a fictional character's sequence of thoughts in the form of a monologue |
| inter | the position of the head of the Department of the Interior |
| inter | the person who holds the secretaryship of the Interior Department |
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