| glass factor | <chemical> Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor xii to xiia. Deficiency of factor xii, also called the hageman trait, leads to increased incidence of thromboembolic disease. Chemical name: Blood-coagulation factor XII (12 Dec 1998) |
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| relaxation factor | Substance presumably involved in the return of muscle fibrils to the resting state after nervous stimulation ceases, postulated to act by withdrawing Calcium from myosin-ATPase sites. (05 Mar 2000) |
| release factor | A component of the specialised transport system involved in the transport of cobalamin (vitamin B12) across the wall of the intestine. Dissociates the complex between cobalamin and the extracellular cobalamin binding glycoprotein known as intrinsic factor. (18 Nov 1997) |
| vitamin B12 with intrinsic factor concentrate | A combination of vitamin B12 with suitable preparations of the mucosa of the stomach or intestine of domestic animals used for food by humans. (05 Mar 2000) |
| glucose tolerance factor | A water-soluble complex containing chromium needed for normal glucose tolerance. (05 Mar 2000) |
| resistance factor | <molecular biology> A self-replicating fragment of nucleic acid that confers drug resistance and is transmitted from one bacterium to another via conjugation. (09 Oct 1997) |
| resistance-inducing factor | An agent from normal chick embryos that interferes with multiplication of the avian leukosis-sarcoma virus, and is seemingly an avirulent leukosis virus antigenically related to the avian leukosis-sarcoma virus. (05 Mar 2000) |
| resistance-transfer factor | The transfer gene of the resistance plasmid. (05 Mar 2000) |
| pellagra-preventing factor | A precursor of NAD, that is a product of the oxidation of nicotine. (18 Nov 1997) |
| Von Willebrand factor | Plasma factor involved in platelet adhesion through an interaction with Factor VIII. See: Von Willebrand disease. (18 Nov 1997) |
| von Willebrand factor-degrading protease | <enzyme> A large protease from normal human plasma that degrades vwf at the 842tyr-843met peptide bond Registry number: EC 3.4.24.- Synonym: vwf-cleaving protease (26 Jun 1999) |
| glycotropic factor | A principle in extracts of the anterior lobe of the hypophysis that raises the blood sugar and antagonises the action of insulin; purified pituitary growth hormone produces an identical effect. Synonym: insulin-antagonizing factor. (05 Mar 2000) |
| melanotropin-releasing factor | A hexapeptide similar to oxytocin; it stimulates the release of melanotropin. Synonym: melanotropin-releasing factor, melanotropin-releasing hormone. Origin: melanotropin + L. Libero, to free, + -in (05 Mar 2000) |
| peptide elongation factor tu | A protein found in bacteria and eukaryotic cells which delivers aminoacyl-trna's to the a site of the ribosome. The aminoacyl-trna is first bound to a complex of elongation factor tu containing a molecule of bound GTP. The resulting complex is then bound to the 70s initiation complex. Simultaneously the GTP is hydrolyzed and a tu-GDP complex is released from the 70s ribosome. The tu-GTP complex is regenerated from the tu-GDP complex by the ts elongation factor and GTP. (12 Dec 1998) |
| gonadotropin-releasing factor | <hormone> The peptide hormone that control reproductive function. It produced and released by the hypothalamus and controls the production and release of gonadotrophins from the pituitary gland. It causes the production of luteinising hormone and follicle-stimulating hormone. Synonym: gonadotropin-releasing factor, gonadotropin-releasing hormone, luteinizing hormone/follicle-stimulating hormone-releasing factor, gonadoliberin. Origin: Gonad + L. Libero, to free, + -in (19 Sep 2002) |