| ascorbic acid | <biochemistry> A requisite in the diet of man and guinea pigs. May act as a reducing agent in enzymic reactions, particularly those catalysed by hydroxylases. Synonym: Vitamin C. (18 Nov 1997) |
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| ascorbic acid deficiency | A condition due to a dietary deficiency of ascorbic acid (vitamin c), characterised by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of haemorrhage. Ascorbic acid deficiency frequently develops into scurvy in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (cecil textbook of medicine, 19th ed, p1177) (12 Dec 1998) |
| asparagine-oxo-acid aminotransferase | <enzyme> Consider also EC 2.6.1.45, serine-glyoxylate aminotransferase, which also acts on asparagine Registry number: EC 2.6.1.14 Synonym: asparagine transaminase (26 Jun 1999) |
| asparaginic acid | <amino acid> One of the twenty naturally occurring amino acids. Has the following chemical characteristics: pKa1 pKa2 pKa3 pI Water Solubility (30deg C)2.09-3.86 9.82 2.97 0.6 (09 Oct 1997) |
| aspartic acid | <amino acid> One of the twenty naturally occurring amino acids. Has the following chemical characteristics: pKa1 pKa2 pKa3 pI Water Solubility (30deg C)2.09-3.86 9.82 2.97 0.6 (09 Oct 1997) |
| aspartic acid 2-oxoglutarate-dependent dioxygenase | <enzyme> Hydroxylates one aspartic acid residue in the first egf-like unit of factor ix Registry number: EC 1.14.11.- Synonym: aspartate 2-oxoglutarate dioxygenase, asp-2-og-dioxygenase, aspartyl beta-hydroxylase, aspartyl (asparaginyl) beta-hydroxylase (26 Jun 1999) |
| aspergillic acid | 2-Hydroxy-3-isobutyl-6-(1-methylpropyl)pyrazine-1-oxide;produced by Aspergillus flavus; an antibiotic agent moderately active against Gram-positive and Gram-negative bacteria, but toxic to animal tissues. (05 Mar 2000) |
| Aspergillus acid proteinase | <enzyme> Included in the group of microbial carboxyl proteinases EC 3.4.23.6; has been sequenced; genbank d87681 Registry number: EC 3.4.23.- Synonym: apfap, aspergillus fumigatus acid proteinase, aspergillus niger acid proteinase, aspergillus awamori acid proteinase (26 Jun 1999) |
| atractosylidic acid | The steroid aglycon and toxic principle of atractylic acid. Synonym: atractosylidic acid, atractylin. (05 Mar 2000) |
| atractylic acid | A highly poisonous steroid glycoside from Atractylis gummifera L. (Compositae), having a strychnine-like action that produces convulsions of a hypoglycaemic nature; the aglycon, atractyliginin, is combined with glucose and isovaleric acid, and is the toxic principle. Atractylic acid interferes with oxidative reactions, the citric acid cycle, and nerve conduction. (05 Mar 2000) |
| aureolic acid | An antibiotic produced by Streptomyces argillaceus and S. Tanashiensis; possesses antineoplastic activity. Synonym: aureolic acid, mitramycin. (05 Mar 2000) |
| aurintricarboxylic acid | <chemical> 5-((3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl)-2-hydroxybenzoic acid. A dye which inhibits protein biosynthesis at the initial stages. The ammonium salt (aluminon) is a reagent for the colourimetric estimation of aluminum in water, foods, and tissues. Chemical name: Benzoic acid, 5-((3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl)-2-hydroxy- (12 Dec 1998) |
| azetidinecarboxylic acid | <chemical> 2-azetidinecarboxylic acid. A proline analog. Acts as a stoichiometric replacement of proline causing the production of abnormal proteins having impaired biological activity. Chemical name: 2-Azetidinecarboxylic acid (12 Dec 1998) |
| Baker's acid haematein | An acidic solution of oxidised haematoxylin used on frozen sections for staining phospholipids. (05 Mar 2000) |
| barbituric acid | <chemistry> A white, crystalline substance, derived from alloxantin, also from malonic acid and urea, and regarded as a substituted urea. Source: Websters Dictionary (01 Mar 1998) |