| ferrochelatase |
[EC 4.99.1.1] a mitochondrial enzyme of the lyase class that catalyzes the insertion of ferrous iron into protoporphyrin IX to form protoheme IX, the heme of hemoglobin. Inhibition of the enzyme in lead poisoning results in accumulation of protoporphyrin IX. Deficiency of the enzyme, an autosomal dominant trait, results in protoporphyria.
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| ferroheme |
the Fe(II) chelate of heme; sometimes called simply heme.
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| ferrokinetic |
pertaining to ferrokinetics.
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| ferrokinetics |
the movement of iron in the body from plasma transferrin to red cell precursors in bone marrow to circulating red cells to macrophages in the reticuloendothelial system and back to plasma transferrin. Ferrokinetic studies, using the radioisotope iron-59 as a tracer, measure kinetic parameters helpful in evaluating certain anemias and in detecting abnormal iron storage or extramedullary hematopoiesis by external counting over the liver, spleen, and bone marrow. Studies include plasma iron clearance half-time, plasma iron turnover, red cell utilization, and erythrocyte iron turnover.
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| ferrosoferric |
combining a ferrous with a ferric compound; containing iron in two different oxidation states, as in the oxide Fe3O4.
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