| folylpolyglutamate synthetase | <enzyme> Catalyze the formation of amide bond between gamma-carboxyl of a folate and amino group of glutamic acid folate; any folic acid including polyglutamates Registry number: EC 6.3.2.17 Synonym: folylpoly-gamma-glutamate synthetase, folylpolyglutamate synthase, tetrahydrofolylpolyglutamate synthase (26 Jun 1999) |
|---|---|
| formyl-methenyl-methylenetetrahydrofolate synthetase | <chemical> Trifunctional enzyme which contains EC 6.3.4.3, formyltetrahydrofolate synthetase, plus EC 3.5.4.9, methenyltetrahydrofolate cyclohydrolase, and EC 1.5.1.5, methylenetetrahydrofolate dehydrogenase as a complex in sheep liver Chemical name: synthetase, formyl-methenyl-methylenetetrahydrofolate Synonym: c1-thf synthase, c1-tetrahydrofolate synthase, formyl-methenyl-methylenetetrahydrofolate synthetase (combined), c-1-tetrahydrofolate synthetase, nadp-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase-synthetase (26 Jun 1999) |
| leupeptin acid synthetase | <enzyme> ATP essential for reaction Registry number: EC 6.3.2.- (26 Jun 1999) |
| lysergyl peptide synthetase | <enzyme> Multifunctional enzyme which forms non-cyclol d-lysergyl peptide lactams; consists of two polypeptide chains - lps 1 binds the 3 amino acids (ala, phe and pro) of the peptide nucleus and lps 2 binds d-lysergic acid Registry number: EC 6.3.2.- Synonym: d-lysergylpeptide synthetase (26 Jun 1999) |
| acetate-CoA ligase | <enzyme> An enzyme that catalyses the formation of CoA derivatives from ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl CoA. It acts also on propionates and acrylates. Chemical name: Acetate:CoA ligase (AMP-forming) Registry number: EC 6.2.1.1 (12 Dec 1998) |
| acetate-succinate CoA-transferase | <enzyme> Tritichomonas and trichomonas enzyme converts acetyl-CoA and succinate to acetate and succinyl-CoA Registry number: EC 2.8.3.- Synonym: acetate-succinate coenzyme a-transferase (26 Jun 1999) |
| acetoacetyl-CoA | Intermediate in the oxidation of fatty acids and in the formation of ketone bodies; also formed from two molecules of acetyl-CoA; major role is condensation with acetyl-CoA to form the important beta-hydroxy-beta-methylglutaryl-CoA. Synonym: acetoacetyl-coenzyme A. (05 Mar 2000) |
| acetoacetyl-CoA reductase | An oxidoreductase catalyzing interconversion of a 3-oxoacyl-CoA and NADPH, and the corresponding d-3-hydroxyacyl-CoA, and NADP+. A step in fatty acid synthesis. (05 Mar 2000) |
| acetoacetyl-CoA thiolase | An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis. Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase. (05 Mar 2000) |
| acetyl-CoA | <enzyme> Condensation product of coenzyme A and acetic acid, symbolised as CoAS~COCH3; intermediate in transfer of two-carbon fragment, notably in its entrance into the tricarboxylic acid cycle and in fatty acid synthesis. This coenzyme plays a huge role in intermediary metabolism, in which cells synthesise, break down or use nutrient molecules for energy production, growth, etc. Acetyl-coenzyme A synthase is found in bacteria and plants and catalyses the reaction in which acetate enters metabolic pathways and forms acetyl-coenzyme A. Synonym: acetyl-coenzyme A, active acetate. (05 Mar 2000) |
| acetyl-CoA-1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase | <enzyme> Transfers acetate from acetyl CoA to the sn-2-position of 1-alkyl-2-lyso-glycerophosphocholine, forming the substrate for 1-alkylglycerophosphocholine acetyltransferase (EC 2.3.1.67) Registry number: EC 2.3.1.- Synonym: acopc acetyltransferase, 1-alkyl-2-lyso-sn-glycero-3-phosphocholine-acetyl CoA acetyltransferase, alkyllyso-gp-acetyl-CoA acetyltransferase, acetyl-coenzyme a-1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase (26 Jun 1999) |
| acetyl-CoA acetyltransferase | An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis. Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase. (05 Mar 2000) |
| acetyl-CoA acylase | <enzyme> An enzyme that catalyses reversibly the hydrolysis of acetyl-CoA to yield CoA and acetate. The enzyme is involved in the oxidation of fatty acids. Chemical name: Acetyl-CoA hydrolase Registry number: EC 3.1.2.1 (12 Dec 1998) |
| acetyl-CoA acyltransferase | <enzyme> An enzyme catalyzing the thioclastic cleavage by coenzyme A of beta-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation. See: acetyl-CoA acetyltransferase. Synonym: 3-ketoacyl-CoA thiolase, beta-ketothiolase. (05 Mar 2000) |
| acetyl-CoA:alpha-glucosaminide acetyltransferase | <enzyme> An enzyme involved in the synthesis of certain carbohydrate moieties on proteins. A deficiency of this enzyme leads to mucopolysaccharidosis type III C. (05 Mar 2000) |