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adenylosuccinate synthase <enzyme> A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyses the synthesis of adenylosuccinate from GTP, imp, and aspartate with the formation of orthophosphate and GDP.
Chemical name: IMP:L-aspartate ligase (GDP-forming)
Registry number: EC 6.3.4.4
(12 Dec 1998)
adenylosuccinic acid A condensation product of aspartic acid and inosine 5'-monophosphate; an intermediate in the biosynthesis of adenylic acid. Formally, it is adenylic acid with succinic acid replacing an H of the NH2 group, forming a C-N.
Synonym: adenylylosuccinic acid, N-succinyladenylic acid.
Acronym: sAMP
(05 Mar 2000)
adenylpyrophosphatase <enzyme> A group of enzymes which catalyze the hydrolysis of ATP coupled with another function such as transporting calcium across a membrane. These enzymes may be dependent on calcium, magnesium, anions, h+, or DNA.
Chemical name: ATP phosphohydrolase
Registry number: EC 3.6.1.3
(12 Dec 1998)
adenylyl The radical of adenylic acid minus an OH from the phosphoric group; often shortened to adenyl in compound names, such as adenylosuccinic acid.
(05 Mar 2000)
adenylyl cyclase The former name for adenylate cyclase.
(05 Mar 2000)
adenylyl imidodiphosphate <chemical> 5'-adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial atpase and also inhibits ATP-dependent reactions of oxidative phosphorylation.
Chemical name: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid
(12 Dec 1998)
adenylyl sulfate-ammonia adenylyltransferase <enzyme> Forms adenosine 5'-phosphoramidate
Registry number: EC 2.7.7.-
Synonym: adenylyl sulphate-ammonia adenylyltransferase, as-aat
(26 Jun 1999)
adenylylosuccinate lyase <enzyme> An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyses the conversion of 5'-phosphoribosyl-4-(n-succinocarboxamide)-5-aminoimidazole to 5'-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP.
Chemical name: N(6)-(1,2-Dicarboxyethyl)AMP AMP-lyase
Registry number: EC 4.3.2.2
(12 Dec 1998)
adenylylosuccinate synthase <enzyme> A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyses the synthesis of adenylosuccinate from GTP, imp, and aspartate with the formation of orthophosphate and GDP.
Chemical name: IMP:L-aspartate ligase (GDP-forming)
Registry number: EC 6.3.4.4
(12 Dec 1998)
adenylylosuccinic acid A condensation product of aspartic acid and inosine 5'-monophosphate; an intermediate in the biosynthesis of adenylic acid. Formally, it is adenylic acid with succinic acid replacing an H of the NH2 group, forming a C-N.
Synonym: adenylylosuccinic acid, N-succinyladenylic acid.
Acronym: sAMP
(05 Mar 2000)
adenylylsulfate kinase adenosine 5'-phosphosulfate kinase
adeps 1. Denoting fat or adipose tissue.
2. The rendered fat of swine, lard, used in the preparation of ointments.
Synonym: lard.
See: adeps lanae.
Origin: L. Lard, fat
(05 Mar 2000)
adeps lanae The greasy substance obtained from the wool of the sheep Ovis aries (family Bovidae). Used as an emollient base for creams and ointments.
Synonym: hydrous wool fat, lanolin, wool wax.
Origin: L. Fat of wool
(05 Mar 2000)
adeps renis An obsolete term for the layer of adipose tissue ("fatty capsule") surrounding the kidney (perirenal fat).
(05 Mar 2000)
ADEPT <pharmacology> A method for targeting a drug to a specific tissue, in which the targeting agent and the drug are administered separately.
The drug is designed to be inactive (a prodrug) until it is converted by an enzyme, which is the targeting agent. The enzyme is coupled to an antibody that directs it to the tissue of interest. When the enzyme arrives at the tissue, the prodrug is activated only at that site, sparing other tissues from potentially toxic side effects.
Acronym: ADEPT
(14 Nov 1997)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 13
  • Adenovirus Early Proteins - »õâ Proteins encoded by adenoviruses that are synthesized prior to, and in the absence of, viral DNA replication. The proteins are involved in both positive and negative regulation of expression in viral and cellular genes, and also affect the stability of viral mRNA. Some are also involved in oncogenic transformation.
    Synonyms : Adenovirus E19 Protein, Adenovirus E29 Protein, E19 Protein, Adenovirus, E19 Proteins, Adenovirus, E29 Protein, Adenovirus, E29 Proteins, Adenovirus, Early Proteins, Adenovirus, Protein, Adenovirus E19, Protein, Adenovirus E29, Proteins, Adenovirus E19
  • Adenovirus Infections, Human - »õâ Respiratory and conjunctival infections caused by 33 identified serotypes of human adenoviruses.
    Synonyms : Human Adenovirus Infections, Infections, Human Adenovirus, Adenovirus Infection, Human, Fever, Pharyngo-Conjunctival, Human Adenovirus Infection, Infection, Human Adenovirus, Pharyngo Conjunctival Fever
  • Adenoviruses, Canine - »õâ Species of the genus MASTADENOVIRUS that causes fever, edema, vomiting, and diarrhea in dogs and encephalitis in foxes. Epizootics have also been caused in bears, wolves, coyotes, and skunks. The official species name is Canine adenovirus and it contains two serotypes.
    Synonyms : Canine Infectious Hepatitis Virus, Canine adenovirus, Hepatitis Virus, Canine, Infectious Canine Hepatitis Virus, Canine Hepatitis Virus, Canine Hepatitis Viruses, Hepatitis Viruses, Canine, Viruses, Canine Hepatitis, adenovirus, Canine
  • Adenoviruses, Human - »õâ Species of the genus MASTADENOVIRUS, causing a wide range of diseases in humans. Infections are mostly asymptomatic, but can be associated with diseases of the respiratory, ocular, and gastrointestinal systems. Serotypes (named with arabic numbers) have been grouped into species designated Human adenovirus A-F.
    Synonyms : APC Virus, Adenovirus, Human, Human Adenovirus, Human Adenoviruses
  • Adenoviruses, Porcine - »õâ Species of the genus MASTADENOVIRUS, causing neurological disease in pigs.
    Synonyms : Adenovirus, Porcine, Porcine Adenovirus
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adenosine A nucleoside combining the base adenine with D-ribose. One of the building blocks of DNA and RNA.
Ãâó: www.amfar.org/cgi-bin/iowa/bridge.html
adenovirus Any virus from the family Adenoviridae. More than 40 adenoviruses are known to infect people, causing upper respiratory tract, gastrointestinal, and eye infections.
Ãâó: www.amfar.org/cgi-bin/iowa/bridge.html
adenine A purine base found in RNA and DNA; in double-stranded DNA adenine pairs with the pyrimidine thymine.
Ãâó: www.modernhumanorigins.com/a.html
adenosine A neurotransmitter that binds to the adenosine receptor. Adenosine is a by-product of ATP metabolism and is an important regulator of sleep. Caffeine is an adenosine antagonist.
Ãâó: science.education.nih.gov/supplements/nih2/addicti...
adenosine diphosphate A compound which upon phosphorylation (addition of phosphate and energy) forms high energy bonds as ATP.
Ãâó: www.pestmanagement.co.uk/lib/glossary/glossary_a.s...
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