| succinate-CoA ligase (GDP-forming) |
[EC 6.2.1.4] an enzyme of the ligase class that catalyzes the cleavage of succinate from succinyl CoA, using the energy so generated to form GTP from GDP. The reaction is part of the tricarboxylic acid cycle (see illustration at cycle). Called also succinyl CoA synthetase.
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| succinate-semialdehyde dehydrogenase |
[EC 1.2.1.24] an enzyme of the oxidoreductase class that catalyzes the oxidation of 4-hydroxybutyric acid to succinate. The reaction is the final step in the inactivation of γ-aminobutyric acid (GABA); when enzyme activity is deficient, increased levels of GABA and 4-hydroxybutyric acid can be detected in urine, plasma, and cerebrospinal fluid.
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| succinic semialdehyde dehydrogenase deficiency |
an autosomal recessive aminoacidopathy caused by deficiency of the enzyme succinate semialdehyde dehydrogenase. The resulting increase in γ-aminobutyric acid and γ-hydroxybutyric acid causes mental retardation, hypotonia, and ataxia. Called also γ- or 4-hydroxybutyricaciduria.
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| succinimide |
1. an organic compound comprising a pyrrole ring with two carbonyl substitutions. 2. any of a class of anticonvulsants with such a basic structure, including ethosuximide, methsuximide, and phensuximide.
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| Succinimonas |
a genus of gram-negative, anaerobic bacteria of the family Bacteroidaceae, made up of motile, short, straight rods with rounded ends that produce large amounts of succinic acid, found in the rumen contents of cattle. The genus contains a single species, S. amyloly´tica.
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