| MTP | maximum tolerated pressure; medial tibial plateau; median time to progression; metacarpophalangeal; ... |
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| NHP | nonhemoglobin protein; nonhistone protein; normal human pooled plasma; Nottingham Health Profile; nu... |
| NSP | neuron specific protein; nonstructural protein |
| OMP | olfactory marker protein; ornithine monophosphate; outer membrane protein |
| PBP | penicillin-binding protein; porphyrin biosynthesis pathway; prostate-binding protein; pseudobulbar p... |
| periplasmic protein disulfide oxidoreductase | <enzyme> Isolated from haemophilus influenzae; may be required for assembly or folding of one or more disulfide-containing cell envelope proteins; ccmg isolated from paracoccus denitrificans Registry number: EC 1.8.4.- Synonym: por disulfide oxidoreductase, por gene product, periplasmic oxidoreductase, ccmg gene product (26 Jun 1999) |
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| ribose binding protein | <protein> Periplasmic binding proteins of bacteria that interact either with the ribose transport system or with the methyl accepting chemotaxis protein MCP III (trg). (18 Nov 1997) |
| ribosomal protein | <protein> Proteins present within the ribosomal subunits. In prokaryotes there are 31 proteins in the large subunit and 21 in the small subunit. Eukaryotic subunits have 50 (large subunit) and 33 (small subunit) proteins. (18 Nov 1997) |
| ribosomal protein s6 kinase | <enzyme> A protein serine/threonine kinase which is involved in cell transformation by polyoma virus and is connected to the expression of igf2. The immunosuppressant rapamycin inhibits the activation of the kinase, leading to reduced translation of certain mRNAs and a decrease in protein synthesis. Registry number: EC 2.7.10.- (12 Dec 1998) |
| ribosomal protein S6 kinase kinase | <enzyme> Isolated from unfertilised xenopus eggs; a 41 kD enzyme that is associated, in vivo, with phosphorylation on threonine and tyrosine residues and, in vitro, with phosphorylation on serine as well Registry number: EC 2.7.1.- Synonym: rsk kinase (26 Jun 1999) |
| chk1 protein kinase | <enzyme> A yeast protein kinase homolog, involved in cell-cycle arrest when DNA damage has occurred or when unligated DNA is present; named chk1 for checkpoint kinase; genbank af016582 (human), af016583 (murine) Registry number: EC 2.7.1.- Synonym: chk1 kinase, chk1 gene product, rad27 protein, rad27 gene product, hchk1 (human), mchk1 (murine), mammalian chk1 (26 Jun 1999) |
| green fluorescent protein | <protein> A protein found in jellyfish which fluoresces, or glows green visible light when excited by UV light with a wavelength of 395 nanometres. It can function as a biological marker when attached to other proteins. The structure of the protein is cylindrical with the glowing component, an amino acid complex called a fluorophore, in the middle of it. (09 Oct 1997) |
| groel protein | A chaperonin 60 heat-shock protein isolated from escherichia coli. (12 Dec 1998) |
| groes protein | A chaperonin 10 heat-shock protein isolated from escherichia coli. (12 Dec 1998) |
| GTPase activating protein | <molecular biology> Originally purified as a 125 kD protein from bovine brain (1044 amino acids), stimulates the GTPase activity of ras p21 and thereby switches it to the inactive state. GAP may itself be regulated by phospholipids and by phosphorylation on a tyrosine residue by growth factor receptors (PDGF R, EGF R). The neurofibromatosis type 1 gene NF1) codes for a protein homologous to GAP. GAP has both SH2 and SH3 domains. Another example is sar 1 (from yeast). (18 Nov 1997) |
| GTP-binding protein | <molecular biology, protein> There are two main classes of G-proteins, the heterotrimeric G proteins that associate with receptors of the seven transmembrane domain superfamily and are involved in signal transduction and the small cytoplasmic G-proteins. Regulatory proteins found in all cells. They are versatile molecular switches, involved in the control of a wide range of biological processes - protein synthesis, signal transduction pathways, growth and differentiation. They all act through a common molecular mechanism based on their ability to bind the guanine nucleotides GTP and GDP selectively and with high affinity. Stimulatory G-proteins are permanently activated by cholera toxin, inhibitory ones by pertussis toxin. Transducin was one of the first of the heterotrimeric G-proteins to be identified. The small G-proteins are a diverse group of monomeric GTPases that include ras, rab, rac and rho and that play an important part in regulating many intracellular processes including cytoskeletal organisation and secretion. Their GTPase activity is regulated by activators (GAPs) and inhibitors (GIPs) that determine the duration of the active state. (12 Jul 2000) |
| RLK5-associated protein phosphatase | <enzyme> Associated with serine-threonine receptor-like kinase, rlk5; from arabidopsis thaliana; composed of 3 domains, an amino-terminal signal anchor, a kinase interaction domain and a type 2c protein phosphatase catalytic domain; mw 65 kD; genbank u09505 Registry number: EC 3.1.3.- Synonym: kapp, kinase-associated protein phosphatase (26 Jun 1999) |
| guanosine triphosphate binding protein | <protein> A type of protein embedded in the cytoplasmic membrane of the cell which transmits signals from outside the cell (such as from hormones binding to receptors on the outside of the cell) to the inside of the cell, where it causes some sort of biochemical reaction within the cell to the signal (such as the altering of metabolic pathways or gene expression). The process by which the protein does this is unclear but involves exchanging a molecule of GDP for a molecule of GTP. (09 Oct 1997) |
| methyl accepting chemotaxis protein | Methyl accepting chemotaxis proteins. Proteins of the inner cytoplasmic face of the bacterial plasma membane with which the receptors of the outer face interact. Four different MCPs are known in E. Coli, each with a separate set of receptors. Can be methylated at various sites, methylation is part of the adaptation to the signal. Although important intermediate signal integration sites, they are not directly connected to the motor. (18 Nov 1997) |
| PfKIN protein kinase | <enzyme> Snf1 type protein kinase from plasmodium flaciparum; genbank z22868 Registry number: EC 2.7.10.- (26 Jun 1999) |