| primary sclerosing cholangitis | <radiology> Idiopathic, associated with IBD (50%), usually UC, M more than F, peak age 20-30 years of age, chronic inflammation and fibrosis of all bile ducts, stricture, obstruction, abscess (string of beads), intramural pseudo-diverticula, cholangiocarcinoma (10%!!), dilatation proximal to stricture may signal carcinoma Differential diagnosis: cholangiocarcinomarcinoma (diffuse form), primary biliary cirrhosis (PBC), AIDS-related cholangitis (? due to CMV) (12 Dec 1998) |
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| primary screw-worm | An obligatory screw-worm that can penetrate normal tissues and feed as a primary invader. The important myiasis flies of man that serve as p. Screw-worm's are Cochliomyia hominivorax, Chrysomyia bezziana, and Wohlfahrtia magnifica. (05 Mar 2000) |
| primary senile dementia | <disease> A progressive, neurodegenerative disease characterised by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. The cause of nerve cell death is unknown but the cells are recognised by the appearance of unusual helical protein filaments in the nerve cells (neurofibrillary tangles) and by degeneration in cortical regions of brain, especially frontal and temporal lobes. Alzheimer's disease is the most common cause of dementia. (22 May 1997) |
| primary sequestrum | A completely detached sequestrum. (05 Mar 2000) |
| primary sex characters | The sex glands, testes or ovaries, and the accessory sex organs. (05 Mar 2000) |
| primary shock | Shock mainly nervous in nature, from pain, anxiety, etc., which ensues almost immediately upon the receipt of a severe injury. (05 Mar 2000) |
| primary skin graft | A skin graft transferred immediately after the creation of a raw area. (05 Mar 2000) |
| primary sodium phosphate | NaH2PO4-H2O;used to increase urinary acidity. Synonym: primary sodium phosphate, sodium acid phosphate, sodium dihydrogen phosphate. (05 Mar 2000) |
| primary spermatocyte | <cell biology> A stage in the differentiation of the male germ cells. Spermatogonia differentiate into primary spermatocytes, showing a considerable increase in size in doing so, primary spermatocytes divide into secondary spermatocytes. (18 Nov 1997) |
| primary structure | The covalent backbone of a macromolecule. The order of subunits in a biological polymer, such as amino acids in a polypeptide or nucleotides in a molecule of DNA or RNA. (09 Oct 1997) |
| primary syphilis | The first stage of syphilis See: syphilis. (05 Mar 2000) |
| primary teeth | <dentistry> The first set of teeth that develop in childhood. Synonym: deciduous teeth. (08 Jan 1998) |
| primary telangiectasia | angioma serpiginosum |
| primary tooth | A tooth of the first set of teeth, comprising 20 in all, that erupts between the mean ages of 6 and 28 months of life. Synonym: dens deciduus, baby tooth, deciduous dentition, dens lacteus, first dentition, milk tooth, primary dentition, primary tooth, temporary tooth. (05 Mar 2000) |
| primary transcript | <molecular biology> RNA transcript immediately after transcription in the nucleus, before RNA splicing or polyadenylation to form the mature mRNA. (18 Nov 1997) |