| ribosomal protein s6 kinase | <enzyme> A protein serine/threonine kinase which is involved in cell transformation by polyoma virus and is connected to the expression of igf2. The immunosuppressant rapamycin inhibits the activation of the kinase, leading to reduced translation of certain mRNAs and a decrease in protein synthesis. Registry number: EC 2.7.10.- (12 Dec 1998) |
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| ribosomal protein S6 kinase kinase | <enzyme> Isolated from unfertilised xenopus eggs; a 41 kD enzyme that is associated, in vivo, with phosphorylation on threonine and tyrosine residues and, in vitro, with phosphorylation on serine as well Registry number: EC 2.7.1.- Synonym: rsk kinase (26 Jun 1999) |
| chk1 protein kinase | <enzyme> A yeast protein kinase homolog, involved in cell-cycle arrest when DNA damage has occurred or when unligated DNA is present; named chk1 for checkpoint kinase; genbank af016582 (human), af016583 (murine) Registry number: EC 2.7.1.- Synonym: chk1 kinase, chk1 gene product, rad27 protein, rad27 gene product, hchk1 (human), mchk1 (murine), mammalian chk1 (26 Jun 1999) |
| green fluorescent protein | <protein> A protein found in jellyfish which fluoresces, or glows green visible light when excited by UV light with a wavelength of 395 nanometres. It can function as a biological marker when attached to other proteins. The structure of the protein is cylindrical with the glowing component, an amino acid complex called a fluorophore, in the middle of it. (09 Oct 1997) |
| groel protein | A chaperonin 60 heat-shock protein isolated from escherichia coli. (12 Dec 1998) |
| groes protein | A chaperonin 10 heat-shock protein isolated from escherichia coli. (12 Dec 1998) |
| GTPase activating protein | <molecular biology> Originally purified as a 125 kD protein from bovine brain (1044 amino acids), stimulates the GTPase activity of ras p21 and thereby switches it to the inactive state. GAP may itself be regulated by phospholipids and by phosphorylation on a tyrosine residue by growth factor receptors (PDGF R, EGF R). The neurofibromatosis type 1 gene NF1) codes for a protein homologous to GAP. GAP has both SH2 and SH3 domains. Another example is sar 1 (from yeast). (18 Nov 1997) |
| RLK5-associated protein phosphatase | <enzyme> Associated with serine-threonine receptor-like kinase, rlk5; from arabidopsis thaliana; composed of 3 domains, an amino-terminal signal anchor, a kinase interaction domain and a type 2c protein phosphatase catalytic domain; mw 65 kD; genbank u09505 Registry number: EC 3.1.3.- Synonym: kapp, kinase-associated protein phosphatase (26 Jun 1999) |
| methyl accepting chemotaxis protein | Methyl accepting chemotaxis proteins. Proteins of the inner cytoplasmic face of the bacterial plasma membane with which the receptors of the outer face interact. Four different MCPs are known in E. Coli, each with a separate set of receptors. Can be methylated at various sites, methylation is part of the adaptation to the signal. Although important intermediate signal integration sites, they are not directly connected to the motor. (18 Nov 1997) |
| PfKIN protein kinase | <enzyme> Snf1 type protein kinase from plasmodium flaciparum; genbank z22868 Registry number: EC 2.7.10.- (26 Jun 1999) |
| MHC class II protein | <protein> The antigen-presenting molecule found primarily on macrophages and B lymphocytes. (09 Oct 1997) |
| MHC class I protein | <protein> The antigen-presenting molecule found on all nucleated vertebrate cells. (09 Oct 1997) |
| phenylthiocarbamoyl protein | Formed by the reaction of phenylisothiocyanate with a terminal alpha-amino group of a peptide or protein See: phenylisothiocyanate, phenylthiohydantoin. Synonym: PhNCS protein, PTC protein. (05 Mar 2000) |
| PhNCS protein | Formed by the reaction of phenylisothiocyanate with a terminal alpha-amino group of a peptide or protein See: phenylisothiocyanate, phenylthiohydantoin. Synonym: PhNCS protein, PTC protein. (05 Mar 2000) |
| microtubule-associated protein 1B kinase | <enzyme> Serine-threonine-specific protein kinase which acts on microtubule-associated protein 1b (map1b); activated by various mitogens; does not act on map2 Registry number: EC 2.7.10.- Synonym: map1b kinase (26 Jun 1999) |