| isocitric acid dehydrogenase | <enzyme> An enzyme of the oxidoreductase class that catalyses the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires magnesium, mn2+; it is activated by ADP, citrate, and calcium, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (the NADP+ enzyme is EC 1.1.1.42.) Chemical name: Isocitrate:NAD+ oxidoreductase (decarboxylating) Registry number: EC 1.1.1.41 (12 Dec 1998) |
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| isoepoxydon dehydrogenase | <enzyme> Interconversion between phyllostine (2-hydroxymethyl-5,6-epoxy-1,4-benzoquinone) and isoepoxydon (4-hydroxy-5,6-epoxycyclohex-2-en-1-one Registry number: EC 1.- (26 Jun 1999) |
| isopiperitenol dehydrogenase | <enzyme> From peppermint; nad-dependent; forms isopiperitenone Registry number: EC 1.1.1.- (26 Jun 1999) |
| isopyridoxal dehydrogenase | <enzyme> Nad+ dependent; from arthrobacter cr-7 grown on pyridoxine; involved in vitamin b6 degradation Registry number: EC 1.1.1.- (26 Jun 1999) |
| oligosaccharide dehydrogenase | <enzyme> Commercial preparation from staphylococcus which catalyses oxidation of reducing sugars such as glucose, galactose, fructose, mannose, maltose, lactose, maltotriose, maltotetraose, maltopentaose and maltohexaose Registry number: EC 1.1.- (26 Jun 1999) |
| omega-hydroxyleukotriene E4 dehydrogenase | <enzyme> Liver microsome enzyme converts omega-hydroxyleukotriene e4 to 20-carboxyleukotriene e4 Registry number: EC 1.1.1.- Synonym: omega-hydroxy-lte4 dehydrogenase, 20-hydroxyleukotriene e4 dehydrogenase (26 Jun 1999) |
| taurine dehydrogenase | <enzyme> Catalyses the dehydrogenation of taurine with the formation of sulfoacetaldehyde, ammonia and a reduced receptor; nature of receptor is not known Registry number: EC 1.4.99.2 Synonym: taurine(acceptor) oxidoreductase (deaminating) (26 Jun 1999) |
| tauropine dehydrogenase | <enzyme> Converts NADH + h+ +pyruvate + taurine to nad + tauropine (n-(d-1-carboxyethyl)taurine) Registry number: EC 1.5.1.- Synonym: tauropine-nad oxidoreductase, rhodoic acid dehydrogenase (26 Jun 1999) |
| testosterone 17 beta-dehydrogenase | <enzyme> Catalyses reversibly the oxidation of testosterone to 4-androstene-3,17-dione in the presence of nad; was mapped to testosterone dehydrogenases (81-93) (see under 17-hydroxysteroid dehydrogenases (81-90); on-line search 17-hydroxysteroid dehydrogenases (81-93), index medicus see testosterone dehydrogenases (91-93) and 17-hydroxysteroid dehydrogenases (81-90) Registry number: EC 1.1.1.63 Synonym: 17 beta-hydroxysteroid-nad+ 17-oxidoreductase (26 Jun 1999) |
| tetracycline 5a(11a)dehydrogenase | <enzyme> Catalyses the oxidation of 7-chloro-5a(11a)-dehydrotetracycline to 7-chlorotetracycline; uses nadp Registry number: EC 1.3.1.- (26 Jun 1999) |
| tetrahydrofolate dehydrogenase | <enzyme> An enzyme of the oxidoreductase class that catalyses the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. Chemical name: 5,6,7,8-Tetrahydrofolate:NADP+ oxidoreductase Registry number: EC 1.5.1.3 (12 Dec 1998) |
| ecdysone dehydrogenase-isomerase | <enzyme> Converts alpha-ecdysone to less active 3-epiecdysone, using NADP Registry number: EC 1.1.1.- (26 Jun 1999) |
| thromboxane dehydrogenase | <enzyme> Converts thromboxane b2 to 11-dehydro-thromboxane b2, but not the reverse reaction; uses nad but not nadp as cofactor; only attacks the 11-hydroxy group of txb2 Registry number: EC 1.1.1.- Synonym: thromboxane b2 dehydrogenase, 11-hydroxythromboxane b2 dehydrogenase, 11-hydroxy-txb2 dehydrogenase (26 Jun 1999) |
| electron-transferring flavoprotein dehydrogenase | <enzyme> System formed of electron-transferring flavoproteins plus EC 1.3.99.2 or EC 1.3.99.3 (butyryl-CoA dehydrogenase or acyl-CoA dehydrogenase) which reduces ubiquinone and other acceptors Registry number: EC 1.- Synonym: etf dehydrogenase, electron transfer flavoprotein-q oxidoreductases, electron transfer flavoprotein-ubiquinone oxidoreductase, etf-uo (26 Jun 1999) |
| trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | <enzyme> Rat liver cytosol enzyme also catalyses 3alpha-hydroxysteroid dehydrogenase activity (EC 1.1.1.50); bphb isolated from pseudomonas Registry number: EC 1.3.1.20 Synonym: acenaphthenol oxidase, dihydrodiol dehydrogenase, bphb gene product, biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (26 Jun 1999) |