| immunoglobulins, j-chain | The immunoglobulin fragments found in the light chain fractions of secretory IgA and polymeric IgM in a ratio of one j chain per one IgA dimer or one IgM pentamer. It is a polypeptide with a molecular weight of about 17 kD and probably serves either to bind the components of the globulins together or to transfer the globulins across membranes. (12 Dec 1998) |
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| immunoglobulins, kappa-chain | One of the light chains of the immunoglobulins with a molecular weight of approximately 22 kD. They constitute about 60% of all light chains and can be recognised serologically as well as by their specific amino acid sequence. (12 Dec 1998) |
| immunoglobulins, lambda-chain | One of the light chains of the immunoglobulins with a molecular weight of approximately 22 kD. They constitute about 40% of all light chains and can be recognised serologically as well as by their specific amino acid sequence. (12 Dec 1998) |
| immunoglobulins, light-chain | Polypeptide chains, consisting of 211 to 217 amino acid residues, isolated from immunoglobulins and having a molecular weight of approximately 22 kD. There are two major types of light chains, kappa and lambda. In man they are found in a ratio of 60% to 40%, respectively. Both chains consist of linear repeating, similar, but not identical, segments of about 110 amino acid residues. In each segment a disulfide bond establishes a tightly folded approximately 60-membered loop or domain. Adjacent domains are linked by less tightly folded regions. Both light chains contain two such domains. Two light and two heavy chains make one immunoglobulin molecule, but both light chains in one ig are of the same type. (12 Dec 1998) |
| immunoglobulins, mu-chain | Heavy chains found in the fab and fc fragments of IgM and having a molecular weight of approximately 72 kD. They contain about 57 amino acid residues arranged in five domains and have more oligosaccharide branches and a higher carbohydrate content than the heavy chains of IgG. (12 Dec 1998) |
| immunoglobulins, surface | Immunoglobulins bound to the surface of lymphocytes. (12 Dec 1998) |
| immunoglobulins, thyroid-stimulating | Autoantibodies that bind to the thyroid-stimulating hormone (tsh) receptor (receptors, thyrotropin) on thyroid epithelial cells. The autoantibodies mimic tsh causing an unregulated production of thyroid hormones characteristic of graves' disease. (12 Dec 1998) |
| immunohematology | That division of haematology concerned with immune, or antigen-antibody reactions and with related changes in the blood. (05 Mar 2000) |
| immunohistochemistry | Histochemical localization of immunoreactive substances using labelled antibodies as reagents. (12 Dec 1998) |
| immunolocalization | Refers to use of immunological techniques, including specific antibody, to identify the location of molecules or structures within cells or tissues. (05 Mar 2000) |
| immunologic | <immunology> Pertaining to immunology. (18 Nov 1997) |
| immunologic and biological factors | A collective grouping for biologically active substances that play a role in the functioning of the immune system and those that show biological or physiological activity. (12 Dec 1998) |
| immunologic capping | The process by which lymphoid cell surface immunoglobulin receptors, when exposed to bivalent anti-ig antibodies, collect in patches and form a cap at one pole of the cell. The caps may then be endocytosed or shed into the environment in the form of antigen-antibody complexes. Capping has also been induced by lectins and antigens. (12 Dec 1998) |
| immunologic deficiency syndromes | Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral. (12 Dec 1998) |
| immunologic diseases | Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated or both. (12 Dec 1998) |
Synonyms : Immunoglobulin Joining Region Peptide Fragments, Ig Joining Region, Joining Region, Immunoglobulin
Synonyms : Immunoglobulin kappa-Chain, kappa-Chain Immunoglobulins, kappa-Immunoglobulin Light Chain, kappa-Immunoglobulin Subgroup VK-12, kappa-Immunoglobulin Subgroup VK-21, Immunoglobulin kappa Chain, Immunoglobulin kappa Chains, Immunoglobulins, kappa Chain
Synonyms : Km Allotypes, Allotype, Immunoglobulin Inv, Allotype, Immunoglobulin Km, Allotype, Inv, Allotype, Km, Allotypes, Immunoglobulin Km, Allotypes, Inv, Allotypes, Km, Immunoglobulin Inv Allotype, Immunoglobulin Km Allotype, Inv Allotype, Inv Allotype, Immunoglobulin
Synonyms : Immunoglobulin lambda-Chain, lambda-1-Immunoglobulin, lambda-2-Immunoglobulin, lambda-Chain Immunoglobulins, lambda-Immunoglobulin Light Chain, lambda-Immunoglobulin Light Chains, lambda-x Immunoglobulin, Chains, lambda-Immunoglobulin Light
Synonyms : Immunoglobulin Light Chain, Immunoglobulin Light-Chain, Light-Chain Immunoglobulins, Chains, Immunoglobulin Light, Immunoglobulins, Light Chain, Light Chain Immunoglobulins, Light Chain, Immunoglobulin, Light Chains, Immunoglobulin, Light-Chain, Immunoglobulin
| immunodeficiency |
The decreased ability of the body to fight infection and disease.
Ãâó: www.stjude.org/glossary
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| immunocompetent |
Having the ability to produce a normal immune response.
Ãâó: www.stjude.org/glossary
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| immunostimulant |
A substance that increases the ability of the immune system to fight infection and disease.
Ãâó: www.stjude.org/glossary
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| immunosuppressant |
a drug that inhibits the activity of the immune system; used to prevent rejection of a transplant organ and in disorders where the body's immune system attacks its own tissues
Ãâó: www.american-depot.com/services/resources_gl_i.asp
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| immunization |
the process of causing immunity by injecting antibodies or provoking the body to make its own antibodies against a certain microorganism
Ãâó: www.american-depot.com/services/resources_gl_i.asp
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