| genes, erbb-2 | Retrovirus-associated DNA sequences (erbb) related to the c-erbb-1 gene and identified by probes from c-erbb-1 or its avian viral homologue v-erbb. The proto-oncogene erbb-2 (c-erbb-2) codes for a protein that has structural features indicative of a growth factor receptor with close similarity to the epidermal growth factor (egf) receptor. Overexpression and amplification of the gene is associated with adenocarcinomas and with poor prognosis in breast carcinomas. The human c-erbb-2 gene is located at 17p12-21 on the short arm of chromosome 17. (12 Dec 1998) |
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| genes, fms | Family of retrovirus-associated DNA sequences (fms) originally isolated from the susan mcdonough strain of feline sarcoma virus (sm-fesv). The proto-oncogene fms (c-fms) codes for a protein (csf-1) that is a member of the transmembrane tyrosine kinase growth factor receptor family. The human c-fms gene is located at 5q33.3 on the long arm of chromosome 5. (12 Dec 1998) |
| genes, fos | Retrovirus-associated DNA sequences (fos) originally isolated from the finkel-biskis-jinkins (fbj-msv) and finkel-biskis-reilly (fbr-msv) murine sarcoma viruses. The proto-oncogene protein c-fos codes for a nuclear protein which is involved in growth-related transcriptional control. The insertion of c-fos into fbj-msv or fbr-msv induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-31 on the long arm of chromosome 14. (12 Dec 1998) |
| genes, fungal | The genetic material of fungi. It includes mating type genes of saccharomyces cerevisiae. (12 Dec 1998) |
| genes, gag | DNA sequences that form the coding region for proteins associated with the viral core in retroviruses. Gag is short for group-specific antigen. (12 Dec 1998) |
| genes, helminth | The hereditary material of helminths. (12 Dec 1998) |
| genes, homeobox | Highly conserved DNA sequences which have been identified in specific gene transcripts ranging from those of drosophila melanogaster to mouse and human. Homeobox genes function, in part, to generate DNA-binding proteins with an evolutionary conserved approximately 60-residue sequence (homeodomain proteins). (12 Dec 1998) |
| genes, immediate-early | Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes where immediate-early referred to transcription immediately following virus integration into the host cell. It is also used to describe cellular genes which are expressed immediately after resting cells are stimulated by extracellular signals such as growth factors and neurotransmitters. (12 Dec 1998) |
| genes, immunoglobulin | Genes encoding the light and heavy chain segments of immunoglobulins. Light chain gene segments are symbolised l-v (variable), j (joining) and c (constant); ig heavy chain segments have, in addition, a diversity (d) gene. Each segment codes for certain amino acids, and each has a different nucleotide sequence; the genes are assembled by a remarkable shuffling of the segments during b lymphocyte maturation. (12 Dec 1998) |
| genes, insect | The hereditary material of insects. (12 Dec 1998) |
| genes, intracisternal a-particle | A family of retrovirus-like genetic elements coding for virus-like particles found regularly in early rodent embryos (2-cell to blastocyst stage), but which, under certain circumstances such as DNA hypomethylation, are transcribed in a wide variety of neoplasms, including plasmacytomas, neuroblastomas, rhabdomyosarcomas, teratocarcinomas, and colon carcinomas. (12 Dec 1998) |
| genes, jun | Retrovirus-associated DNA sequences (jun) originally isolated from the avian sarcoma virus 17 (asv 17). The proto-oncogene jun (c-jun) codes for a nuclear protein which is involved in growth-related transcriptional control. Insertion of c-jun into asv-17 or the constitutive expression of the c-jun protein produces tumourgenicity. The human c-jun gene is located at 1p31-32 on the short arm of chromosome 1. (12 Dec 1998) |
| genes, lethal | Genes which result in the premature death of the organism; dominant lethal genes kill heterozygotes, whereas recessive lethal genes kill only homozygotes. (12 Dec 1998) |
| genes, mcc | Tumour suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with the formation of colourectal cancer (mcc stands for mutated in colourectal cancer). (12 Dec 1998) |
| genes, mdr | Genes responsible for multidrug resistance resulting from their overexpression in mammalian cells. Mammalian p-glycoproteins are encoded by small mdr gene familes. The human multidrug resistance 1 (mdr1) gene responds to environmental stress including various anticancer agents. It is a major determinant in the development of resistance to a large number of cancer chemotherapeutic agents. (biochem biophys res commun 1994;199(3):1428-35; cancer res 1994:54(6):1536-41) (12 Dec 1998) |
Synonyms : Generalizations, Stimulus, Stimulus Generalization, Stimulus Generalizations
Synonyms : Cistron, Gene, Genetic Materials, Cistrons, Genetic Material, Material, Genetic, Materials, Genetic
Synonyms : abl Oncogene, bcr-abl Proto-Oncogenes, bcr-v-abl Oncogenes, c-abl Proto-Oncogenes, v-abl Oncogenes, Gene, abl, Gene, c-abl, Gene, v-abl, Genes, c-abl, Genes, v-abl, Oncogene, abl, Oncogene, bcr-v-abl, Oncogene, v-abl, Oncogenes, abl, Oncogenes, bcr-v-abl, abl Gene
Synonyms : APC Gene, APC Genes, Gene, APC
Synonyms : Locus, araC Regulator, araC Regulator Locus, Gene, araC, araC Gene
| generalization |
Generalization is an inference rule of Predicate Calculus which states that:"Generalization" can be abbreviated as GEN, and the inference rule can be summarized as the sequentbut this gives rise to an important restriction: the Deduction Theorem cannot be applied to it to deriveThis formula is wrong because x has an unbound instance in its antecedent and a bound occurrence in its consequent, so that if the formula were instead correct, then its free instance of x could be replaced by any ...
Ãâó: en.wikipedia.org/wiki/Generalization_(logic)
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| general paresis |
General paresis of the insane, also known as paralytic dementia, is now known to be a result of syphilis. It had been considered a psychiatric disorder during the nineteenth century, and was extremely common and completely devastating. While retrospective studies have found earlier instances of what may have been the same disorder, the first clearly identified examples of paresis among the insane were described in Paris after the Napoleonic Wars. ...
Ãâó: en.wikipedia.org/wiki/General_paresis
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| generalized anxiety disorder |
General anxiety disorder or generalized anxiety disorder (GAD) is an anxiety disorder that is characterized by uncontrollable worry about everyday things. The frequency, intensity, and duration of the worry are disproportionate to the actual source of worry, and such worry often interferes with daily functioning. GAD sufferers often uncontrollably worry over things such as their job, their finances, and the health of themselves and their family. ...
Ãâó: en.wikipedia.org/wiki/Generalized_anxiety_disorder
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| genetic testing |
Genetic testing allows the genetic diagnosis of vulnerabilities to inherited diseases, and can also be used to determine a person's ancestry. Every person carries two copies of every gene, one inherited from their mother, one inherited from their father. The human genome is believed to contain about 25,000 genes. ...
Ãâó: en.wikipedia.org/wiki/Genetic_testing
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| genetic disease |
A genetic disorder, or genetic disease is a disease caused, at least in part, by the genes of the person with the disease. There are a number of possible causes for genetic defects: * They may be caused by random mutation. * There are genetic disorders caused by the accidental duplication of a chromosome, as in Down syndrome and Klinefelter's syndrome, or repeated duplication of part of a chromosome as in Fragile X syndrome. ...
Ãâó: en.wikipedia.org/wiki/Genetic_disease
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| gene | the total of inherited attributes |
|---|---|
| gene | the technology of preparing recombinant DNA in vitro by cutting up DNA molecules and splicing together fragments from more than one organism |
| gene | the procedure of analyzing the DNA in samples of a person's body tissue or body fluid for the purpose of identification |
| gene | graphical representation of the arrangement of genes on a chromosome |
| gene | a specific gene that produces a recognizable trait and can be used in family or population studies |
| gene | (genetics) any event that changes genetic structure |
| gene | the procedure of analyzing the DNA in samples of a person's body tissue or body fluid for the purpose of identification |
| gene | the branch of psychology that studies the social and mental development of children |
| gene | the branch of biology that studies heredity and variation in organisms |
| gene | analyzing a group of people to determine genetic susceptibility to a particular disease |
| gene | of or relating to the science of genetics |
| gene | by genetic mechanisms |
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