| progesterone reductase | <enzyme> An enzyme that catalyses the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of NAD. It converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione.45. Chemical name: 3 beta-Hydroxy-delta(5)-steroid:NAD+ 3-oxidoreductase Registry number: EC 1.1.1.145 (12 Dec 1998) |
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| sarcosine reductase | <enzyme> Involved in sarcosine metabolism in eubacterium acidaminophilum Registry number: EC 1.4.4.- Synonym: n-methylglycine reductase (26 Jun 1999) |
| prostaglandin-E2 9-reductase | <enzyme> Catalyses reversibly an nad+ dependent oxidation of the 9alpha-hydroxyl group of 15-keto-13,14-dihydro-pgf2alpha to 15-keto-13,14-dihydro-pge2; also acts on pga1; sequence data indicates that it is identical with carbonyl reductase (NADPH) (EC 1.1.1.184) Registry number: EC 1.1.1.189 Synonym: 9-ketoprostaglandin reductase, prostaglandin-9-hydroxydehydrogenase, pge2 9-ketoreductase, pge 9-ketoreductase, prostaglandin e2-9-oxoreductase, prostaglandin 9-ketoreductase, prostaglandin e2-9-ketoreductase, 9-hydroxy-pg dehydrogenase, 9-hydroxyprostaglandin dehydrogenase, pge2 9-reductase (26 Jun 1999) |
| protein disulfide reductase (glutathione) | <enzyme> An enzyme that catalyses the reduction of a protein-disulfide in the presence of glutathione, forming a protein-dithiol. Insulin is one of its substrates. Chemical name: Glutathione:protein-disulfide oxidoreductase Registry number: EC 1.8.4.2 (12 Dec 1998) |
| heterodisulfide reductase | <enzyme> A two-subunit cytochrome b-containing enzyme from methanol-grown methanosarcina barkeri; catalyses the terminal step in the energy-conserving electron transport chain in methanogenic archaea; has been sequenced; authors give EC number as 1.99.4.- (not in enzyme nomenclature) Registry number: EC 1.12.99.- (26 Jun 1999) |
| xylulose reductase | <enzyme> An enzyme that reversibly converts xylulose to xylitol using either NADH (d-xylulose reductase) or NADPH (l-xylulose reductase); a deficiency of the l-form is seen in individuals with essential pentosuria. Synonym: xylitol dehydrogenase. (05 Mar 2000) |
| HMG CoA reductase inhibitor | Drugs, such as lovastatin and pravastatin, which interfere with the biosynthesis of cholesterol; used to treat hyperlipidemia. (05 Mar 2000) |
| HMG-CoA reductase phosphatase | <enzyme> Similar to phosphoprotein phosphatase, EC 3.1.3.16 Registry number: EC 3.1.3.- Synonym: 3-hydroxy-3-methylglutaryl coenzyme a reductase phosphatase (26 Jun 1999) |
| selenate reductase | <enzyme> Terminal electron acceptor for anaerobic respiration in thauera selenatis; reduces selenate to selenite Registry number: EC 1.97.- (26 Jun 1999) |
| pyrroline-2-carboxylate reductase | An oxidoreductase reducing 1-pyrroline-2-carboxylate to l-proline with NAD(P)H. Synonym: proline dehydrogenase, proline oxidase. (05 Mar 2000) |
| pyrroline-5-carboxylate reductase | An oxidoreductase reversibly reducing 1-pyrroline-5-carboxylate to l-proline with NAD(P)H; a deficiency of this enzyme is associated with type I hyperprolinaemia. Synonym: proline dehydrogenase, proline oxidase. (05 Mar 2000) |
| hydrogensulfite reductase | <enzyme> Catalyses the reduction of sulfite mainly to trithionate with concomitant formation of thiosulfate and sulfide in the dissimilatory sulfate reduction pathway; see also trithionate reductase system Registry number: EC 1.8.99.3 Synonym: bisulfite reductase, dissimilatory sulfite reductase, desulfoviridin, desulforubidin, desulfofuscidin (26 Jun 1999) |
| hydroxymethylglutaryl-CoA reductase inhibitors | Compounds that inhibit hmg-CoA reductases. They have been shown to directly lower cholesterol synthesis. (12 Dec 1998) |
| sodium-translocating NADH-quinone reductase | <enzyme> From vibrio alginolyticus; na+ dependent activation is located in the NADH-quinone reductase segment; reduces ubiquinone-1 to ubisemiquinones or ubiquinol; strongly inhibited by 2-n-heptyl-4-hydroxyquinoline n-oxide; do not confuse with sodium independent NADH-quinone reductase EC 1.6.99.2 Registry number: EC 1.6.5.- Synonym: nqr-1, na-translocating NADH-quinone reductase, nqr gene product (26 Jun 1999) |
| S-phenacylglutathione reductase | <enzyme> Toxic alpha-haloketones react nonenzymatically to form s-phenacylglutathione which is reduced to the corresponding non-toxic alkylketone Registry number: EC 1.8.4.- (26 Jun 1999) |