| diseases, single-gene | Hereditary disorders caused by a change (mutation) in a single gene. There are thousands of single-gene diseases including achondroplastic dwarfism, Huntington disease, cystic fibrosis, sickle cell disease, Duchenne muscular dystrophy, and haemophilia. Single-gene diseases typically describe classic simple Mendelian patterns of inheritance (as autosomal dominant, autosomal recessive, and X-linked traits) by comparison with polygenic diseases. (12 Dec 1998) |
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| DNAa gene | <molecular biology> A defective gene of the bacteria Escherichia coli which produces a defective protein that influences DNA replication. (09 Oct 1997) |
| DNAb gene | <molecular biology> A gene found in the bacteria Escherichia coli which makes a protein that is involved in the formation of primer polynucleotide chains, which are precursors of DNA replication. (09 Oct 1997) |
| DNAe gene | <molecular biology> A gene found in the bacteria Escherichia coli which makes some of the components of the DNA Polymerase III protein, an enzyme which plays an important role in DNA replication. (09 Oct 1997) |
| DNAf gene | <molecular biology> A gene which codes for an enzyme (ribonucleotide reductase) which breaks down ribonucleotides. (09 Oct 1997) |
| DNA gene | <molecular biology> Any of a number of genes found in the bacteria Escherichia coli which makes proteins that are essential for DNA replication. (09 Oct 1997) |
| DNAg gene | <molecular biology> A gene found in the bacteria Escherichia coli which makes the enzyme primase, an enzyme which helps make primers, which are precursors to DNA replication. (09 Oct 1997) |
| DNAh gene | <molecular biology> A gene found in the bacteria Escherichia coli which makes some of the components of the DNA Polymerase III protein, an enzyme which plays an important role in DNA replication. (09 Oct 1997) |
| DNAi gene | <molecular biology> A gene that makes a protein which plays a role in DNA replication. (09 Oct 1997) |
| DNAj gene | <molecular biology> A gene found in the bacteria Escherichia coli which helps the bacteria survive at high temperatures. It also plays an important role in the replication of the DNA of bacteriophage lambda. It is closely linked with the DNAK gene. (09 Oct 1997) |
| DNAk gene | <molecular biology> A gene found in the bacteria Escherichia coli which helps the bacteria survive at high temperatures. It also is important in the replication of the DNA of bacteriophage lambda. It is closely linked with the DNAJ gene. (09 Oct 1997) |
| DNAl gene | <molecular biology> A type of DNA gene which has not been described. (09 Oct 1997) |
| DNAq gene | <molecular biology> A gene found in the bacteria Escherichia coli which makes some of the components of the DNA Polymerase III protein, an enzyme with an important role in DNA replication. (09 Oct 1997) |
| DNA repair gene | A gene engaged in DNA repair. When a DNA repair gene is altered, mutations pile up throughout the DNA. (12 Dec 1998) |
| DNAt gene | <molecular biology> A gene that helps dismantle the replication complex (the combination of proteins and enzymes which work together to replicate the DNA) when the end of the DNA molecule has been reached and replication is finished. (09 Oct 1997) |