| transmissible venereal tumour | A rapidly growing, soft, easily bleeding, infectious, connective tissue tumour occurring in the vagina of the female dog and on the penis and sheath of the male; ordinarily transmitted by coitus. Synonym: transmissible venereal tumour. (05 Mar 2000) |
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| triton tumour | A peripheral nerve tumour with striated muscle differentiation, seen most often in neurofibromatosis; named after Masson's theory of transformation of motor nerve fibres into muscle in triton salamanders. (05 Mar 2000) |
| Erdheim tumour | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
| trophoblastic tumour | <oncology, tumour> A malignant and rapidly growing tumour which arises from foetal tissue. The preceding factor is a hydatidiform mole. Symptoms include continued vaginal bleeding in a women with a recent history of hydatidiform mole, abortion or term pregnancy. (27 Sep 1997) |
| trophoblastic tumour, placental site | A tumour that arises from the trophoblast of the placental bed and is composed mainly of cytotrophoblastic cells. It encompasses lesions of low- and high-grade malignancy. (holland et al., cancer medicine, 3d ed, p1691) (12 Dec 1998) |
| tumour | 1. <oncology> An abnormal mass of tissue that results from excessive cell division that is uncontrolled and progressive, also called a neoplasm. Tumours perform no useful body function. They may be either benign (not cancerous) or malignant. 2. Swelling, one of the cardinal signs of inflammations, morbid enlargement. Origin: L. Tumere = to swell (12 May 1997) |
| tumour angiogenesis factor | <growth factor> Substance released from a tumour that promotes vascularisation of the mass of neoplastic cells. Once a tumour becomes vascularised, it will grow more rapidly and is more likely to metastasise. TAF is almost certainly more than one substance. See: angiogenin. (18 Nov 1997) |
| tumour angiogenic factor | A substance released by solid tumours which induces formation of new blood vessels to supply the tumour. (05 Mar 2000) |
| tumour antigens | Antigens that may be frequently associated with tumours or may be specifically found on tumour cells of the same origin (tumour specific), tumour antigens may also be associated with replication and transformation by certain DNA tumour viruses, including adenoviruses and papovaviruses. Synonym: neoantigens. See: T antigens. (05 Mar 2000) |
| tumour-associated antigen | Antigens that are highly correlated with certain tumour cells. They are not usually found, or are found to a lesser extent, on normal cells. (05 Mar 2000) |
| tumour burden | <oncology> The size of the tumour or number of abnormal cells in the organ or tissue. (16 Dec 1997) |
| tumour cell | <oncology> Cell derived from a tumour in an animal. Refers to a tumour causing malignant cell and not an adventitious normal cell. Loosely, a transformed cell able to give rise to tumours. (18 Nov 1997) |
| tumour cells, cultured | Cells grown in vitro from neoplastic tissue for use in studying the proliferative and metabolic capacities of tumour cells, in predicting clinical responses to chemotherapy, in screening new antitumour agents, and in basic biological research. They include carcinoma cell lines. (12 Dec 1998) |
| tumour debulking | Surgically removing as much of the tumour as possible. (12 Dec 1998) |
| tumour embolism | Embolism by neoplastic tissue transported from a tumour site and which may grow as a metastasis. (05 Mar 2000) |