| beta-glucosyl-hydroxymethylcytosine-alpha-glucosyltransferase | <enzyme> Generates gentobiosyl groups on the hydroxymethylcytosine of phage t2 and t6 DNA Registry number: EC 2.4.1.- Synonym: b-glc-hmc-a-glucosyltransferase (26 Jun 1999) |
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| bile acid 7 alpha-dehydroxylase | <enzyme> Mechanism is questionable: cholic acid - deoxycholic acid - chenodeoxycholic acid - lithocholic acid Registry number: EC 1.14.- Synonym: 7 alpha-dehydroxylase, bile acid 7-dehydroxylase, bile acid 7-alpha-dehydroxylase, bai a1, bai a2, bai a3, cholic acid 7alpha-dehydroxylase (26 Jun 1999) |
| galactosyl(alpha 1-4)galactosylceramide galactosyl hydrolase | <enzyme> Active in pH 3.0 component of human plasma (pn-a-2); greatly decreased in fabry's disease Registry number: EC 3.2.1.- Synonym: digalactosylceramidase (26 Jun 1999) |
| maltobionate alpha-glucosidase | <enzyme> An intracellular enzyme capable of hydrolyzing maltobionic acid; from alkalophilic bacillus sp. N-1053 Registry number: EC 3.2.1.- Synonym: maltobionate alpha-d-glucohydrolase (26 Jun 1999) |
| mannosylglycoprotein alpha-1,2-galactosyltransferase | <enzyme> From schizosaccharomyes pompe golgi apparatus; transfers galactose from udpgal to form an alpha 1,2-galactosyl mannoside linkage Registry number: EC 2.4.1.- Synonym: man-1,2-galt (26 Jun 1999) |
| mannosyl-oligosaccharide 1,2-alpha-mannosidase | <enzyme> Cleaves off terminal alpha-1,2-linked mannose residues resulting in the oligosaccharide man(9)glcnac(2) Registry number: EC 3.2.1.113 Synonym: alpha-d-mannosidase I, mannosidase I, man9-mannosidase, man9-alpha-mannosidase, alpha 1,2-mannosidase, 1,2-alpha-d-mannosidase, msds protein (26 Jun 1999) |
| mannosyl-oligosaccharide 1,3 - 1,6-alpha-mannosidase | <enzyme> Removes alpha-1,3- and alpha-1,6-mannosyl residues during post-translational modification of glycoproteins; amino acid sequence of gmii (drosophila) given in second source; genbank x77652 Registry number: EC 3.2.1.114 Synonym: mannosidase II, alpha-d-mannosidase II, 1,3-(1,6-)mannosyl-oligosaccharide alpha-d-mannohydrolase, golgi alpha-mannosidase II, gmii gene product (26 Jun 1999) |
| gene rearrangement, alpha-chain T-cell antigen receptor | Ordered rearrangement of T-cell variable gene regions coding for the alpha-chain of antigen receptors. (12 Dec 1998) |
| genes, T-cell receptor alpha | DNA sequences encoding the alpha chain of the T-cell receptor. The genomic organization of the tcr alpha genes is essentially the same in all species and is similar to the organization of ig genes. (12 Dec 1998) |
| receptors, adrenergic, alpha | One of the two major pharmacological subdivisions of adrenergic receptors. The alpha-beta distinction was originally based on cellular effects of receptor activation but now relies on the relative affinities for certain synthetic ligands. Alpha-adrenergic receptors are further subdivided into several subclasses based on studies of endogenous and cloned receptors. (12 Dec 1998) |
| receptors, adrenergic, alpha-1 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-1 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist phenylephrine and the antagonist prazosin. They are widespread, with clinically important concentrations in the liver, the heart, vascular, intestinal, and genitourinary smooth muscle, and the central and peripheral nervous systems. (12 Dec 1998) |
| receptors, adrenergic, alpha-2 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-2 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist clonidine and the antagonist yohimbine. They are found on pancreatic beta cells, platelets, and vascular smooth muscle, as well as both pre- and postsynaptically in the central and peripheral nervous systems. (12 Dec 1998) |
| receptors, antigen, T-cell, alpha-beta | T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognise antigens only when presented in association with major histocompatibility (MHC) molecules. (12 Dec 1998) |
| maternal serum alpha-fetoprotein | A plasma protein, alpha-fetoprotein (afp) is normally produced by the foetus. The level of afp in the blood serum of pregnant women provides a screening test for open neural tube defects (anencephaly and spina bifida) and for down syndrome (and other chromosome abnormalities). The maternal serum afp (msafp) tends to be unusally high with open neural tube defects and unsually low with down syndrome. (12 Dec 1998) |
| glucan 1,4-alpha-glucosidase | <enzyme> An enzyme that catalyses the hydrolysis of terminal 1,4-linked alpha-d-glucose residues successively from non-reducing ends of polysaccharide chains with the release of beta-glucose. It is also able to hydrolyze 1,6-alpha-glucosidic bonds when the next bond in sequence is 1,4. Chemical name: 1,4-alpha-D-Glucan glucohydrolase Registry number: EC 3.2.1.3 (12 Dec 1998) |