| adenyl cyclase | <enzyme> An enzyme that converts adenosine monophosphate to cyclic adenosine monophosphate, an intracellular second messenger of neural or hormonal activation. (05 Mar 2000) |
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| adenylate | Salt or ester of adenylic acid. (05 Mar 2000) |
| adenylate cyclase | <enzyme> Enzyme responsible for the ATP. (06 May 1997) |
| adenylate kinase | <enzyme> An enzyme that catalyses the phosphorylation of AMP to ADP in the presence of ATP or inorganic triphosphate. Chemical name: ATP:AMP phosphotransferase Registry number: EC 2.7.4.3 (12 Dec 1998) |
| adenylic acid | A condensation product of adenosine and phosphoric acid; a nucleotide found among the hydrolysis products of all nucleic acids. 3'-Adenylic acid (adenosine 3'-monophosphate) and 5'-adenylic acid (adenosine 5'-monophosphate) differ in the place of attachment of the phosphoric acid to the d-ribose; deoxyadenylic acid differs in having H instead of OH at the 2' position of d-ribose. See: AMP. Synonym: adenine nucleotide. (05 Mar 2000) |
| adenylic acid deaminase | <enzyme> An enzyme that catalyses the deamination of AMP to imp. Chemical name: AMP aminohydrolase Registry number: EC 3.5.4.6 (12 Dec 1998) |
| adenylic acid kinase | <enzyme> An enzyme that catalyses the phosphorylation of AMP to ADP in the presence of ATP or inorganic triphosphate. Chemical name: ATP:AMP phosphotransferase Registry number: EC 2.7.4.3 (12 Dec 1998) |
| adenylosuccinase | <enzyme> An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyses the conversion of 5'-phosphoribosyl-4-(n-succinocarboxamide)-5-aminoimidazole to 5'-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP. Chemical name: N(6)-(1,2-Dicarboxyethyl)AMP AMP-lyase Registry number: EC 4.3.2.2 (12 Dec 1998) |
| adenylosuccinate lyase | <enzyme> An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyses the conversion of 5'-phosphoribosyl-4-(n-succinocarboxamide)-5-aminoimidazole to 5'-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP. Chemical name: N(6)-(1,2-Dicarboxyethyl)AMP AMP-lyase Registry number: EC 4.3.2.2 (12 Dec 1998) |
| adenylosuccinate synthase | <enzyme> A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyses the synthesis of adenylosuccinate from GTP, imp, and aspartate with the formation of orthophosphate and GDP. Chemical name: IMP:L-aspartate ligase (GDP-forming) Registry number: EC 6.3.4.4 (12 Dec 1998) |
| adenylosuccinic acid | A condensation product of aspartic acid and inosine 5'-monophosphate; an intermediate in the biosynthesis of adenylic acid. Formally, it is adenylic acid with succinic acid replacing an H of the NH2 group, forming a C-N. Synonym: adenylylosuccinic acid, N-succinyladenylic acid. Acronym: sAMP (05 Mar 2000) |
| adenylpyrophosphatase | <enzyme> A group of enzymes which catalyze the hydrolysis of ATP coupled with another function such as transporting calcium across a membrane. These enzymes may be dependent on calcium, magnesium, anions, h+, or DNA. Chemical name: ATP phosphohydrolase Registry number: EC 3.6.1.3 (12 Dec 1998) |
| adenylyl | The radical of adenylic acid minus an OH from the phosphoric group; often shortened to adenyl in compound names, such as adenylosuccinic acid. (05 Mar 2000) |
| adenylyl cyclase | The former name for adenylate cyclase. (05 Mar 2000) |
| adenylyl imidodiphosphate | <chemical> 5'-adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial atpase and also inhibits ATP-dependent reactions of oxidative phosphorylation. Chemical name: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid (12 Dec 1998) |