| paget disease of breast | <radiology> Form of ductal carcinoma, associated with eczematous changes of the nipple (12 Dec 1998) |
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| Paget's cells | Relatively large, neoplastic epithelial cell's (carcinoma cell's) with hyperchromatic nuclei and palely staining cytoplasm; in Paget's disease of the breast, such cell's occur in neoplastic epithelium in the ducts and in the epidermis of the nipple, areola, and adjacent skin. (05 Mar 2000) |
| Paget's disease | <disease, rheumatology> This is a disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue. Many patients are asymptomatic and diagnosed by routine X-rays. (13 Nov 1997) |
| Paget's disease of the nipple | <oncology, tumour> A cancer of the nipple. (16 Dec 1997) |
| paget's disease, extramammary | A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (devita jr et al., cancer: principles & practice of oncology, 3d ed, p1478) (12 Dec 1998) |
| paget's disease, mammary | An intraductal carcinoma of the breast extending to involve the nipple and areola, characterised clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells (paget's cells). (12 Dec 1998) |
| Paget, Sir James | <person> English surgeon, 1814-1899. See: Paget's cells, Paget's disease, extramammary Paget disease, Paget-von Schrotter syndrome. (05 Mar 2000) |
| Paget-Eccleston stain | <technique> An aldehyde-thionin-PAS-orange G staining technique modified to identify seven different cell types in the anterior pituitary gland. (05 Mar 2000) |
| Paget-von Schrotter syndrome | <syndrome> Stress thrombosis or spontaneous thrombosis of the subclavian or axillary vein; a thoracic-outlet syndrome. Synonym: effort-induced thrombosis. (05 Mar 2000) |
| pagetic | Relating to or suffering from Paget's disease. (05 Mar 2000) |
| pagetoid | Resembling or characteristic of Paget's disease. (05 Mar 2000) |
| pagetoid cells | Atypical melanocytes resembling Paget's cells, found in some cutaneous melanomas of the superficial spreading type. (05 Mar 2000) |
| pagetoid reticulosis | A benign localised form of lymphoma with solitary or closely grouped cutaneous tumours consisting of predominantly epidermal infiltration of mononuclear cells resembling those found in mycosis fungoides. Synonym: pagetoid reticulosis. (05 Mar 2000) |
| pagina | Origin: L. <botany> The surface of a leaf or of a flattened thallus. Source: Websters Dictionary (01 Mar 1998) |
| pagoda cell | <biology> Ganglion cells, from the central nervous system of a leech, with a spontaneous firing pattern that can look a little like a pagoda on an oscilloscope. (18 Nov 1997) |