| isochromosomes | Metacentric chromosomes produced during meiosis or mitosis when the centromere splits transversely instead of longitudinally. The chromosomes produced by this abnormal division are one chromosome having the two long arms of the original chromosome, but no short arms, and the other chromosome consisting of the two short arms and no long arms. Each of these isochromosomes constitutes a simultaneous duplication and deletion. (12 Dec 1998) |
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| isochronal | Uniform in time; of equal time; performed in equal times; recurring at regular intervals; isochronal vibrations or oscillations. See: Isochronous. Source: Websters Dictionary (01 Mar 1998) |
| isochronia | 1. The state of having the same chronaxie. 2. Agreement, with respect to time, rate, or frequency, between processes. Origin: iso-+ G. Chronos, time (05 Mar 2000) |
| isochronous | Occurring during the same time. (05 Mar 2000) |
| isochroous | <optics> Having the same colour; connecting parts having the same colour, as lines drawn through certain points in experiments on the chromatic effects of polarized light in crystals. Source: Websters Dictionary (01 Mar 1998) |
| isocitrase | <enzyme> A key enzyme in the glyoxylate cycle. It catalyses the conversion of isocitrate to succinate and glyoxylate. Chemical name: Isocitrate glyoxylate-lyase Registry number: EC 4.1.3.1 (12 Dec 1998) |
| isocitrate | <biochemistry> An intermediate in the tricarboxylic acid cycle (citric acid cycle). (18 Nov 1997) |
| isocitrate dehydrogenase | <enzyme> An enzyme of the oxidoreductase class that catalyses the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires magnesium, mn2+; it is activated by ADP, citrate, and calcium, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (the NADP+ enzyme is EC 1.1.1.42.) Chemical name: Isocitrate:NAD+ oxidoreductase (decarboxylating) Registry number: EC 1.1.1.41 (12 Dec 1998) |
| isocitrate lyase | <enzyme> A key enzyme in the glyoxylate cycle. It catalyses the conversion of isocitrate to succinate and glyoxylate. Chemical name: Isocitrate glyoxylate-lyase Registry number: EC 4.1.3.1 (12 Dec 1998) |
| isocitric acid | HOOCCH2CH(COOH)CH(OH)COOH;an intermediate in the tricarboxylic acid cycle. (05 Mar 2000) |
| isocitric acid dehydrogenase | <enzyme> An enzyme of the oxidoreductase class that catalyses the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires magnesium, mn2+; it is activated by ADP, citrate, and calcium, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (the NADP+ enzyme is EC 1.1.1.42.) Chemical name: Isocitrate:NAD+ oxidoreductase (decarboxylating) Registry number: EC 1.1.1.41 (12 Dec 1998) |
| isocitritase | <enzyme> A key enzyme in the glyoxylate cycle. It catalyses the conversion of isocitrate to succinate and glyoxylate. Chemical name: Isocitrate glyoxylate-lyase Registry number: EC 4.1.3.1 (12 Dec 1998) |
| isocline | A line in a geographical region that joins all points at which in a population there is the same average frequency for the various alleles at a genetic locus. See: cline. Origin: iso-+ G. Klino, to slope (05 Mar 2000) |
| isoclinic | <physics> Of or pertaining to, or indicating, equality of inclination or dip; having equal inclination or dip. Isoclinal lines, lines on the earth's surface connecting places at which a dipping needle indicates the same inclination or dip. Origin: Iso- + Gr. To incline. Source: Websters Dictionary (01 Mar 1998) |
| isoconazole | Antibacterial and antifungal agent related to ketoconazole and oxiconazole. (05 Mar 2000) |