| immunodeficiency syndrome | <syndrome> An immunological deficiency or disorder, of which the chief symptom is an increased susceptibility to infection, the pattern of susceptibility being dependent upon the kind of deficiency. See: immunodeficiency. (05 Mar 2000) |
|---|---|
| immunodeficiency virus, bovine | A species of lentivirus, subgenus bovine lentiviruses (lentiviruses, bovine), found in cattle and causing lymphadenopathy, lymphocytosis, central nervous system lesions, progressive weakness, and emaciation. It has immunological cross-reactivity with other lentiviruses including HIV. (12 Dec 1998) |
| immunodeficiency virus, feline | A species of lentivirus, subgenus feline lentiviruses (lentiviruses, feline) isolated from cats with a chronic wasting syndrome, presumed to be immune deficiency. There is no antigenic relationship between fiv and HIV, nor does fiv grow in human T-cells. (12 Dec 1998) |
| immunodeficiency with elevated IgM | Immunodeficiency with reduced IgG and IgA-bearing cells; there is recurrent pyogenic infection; X-linked in some families. (05 Mar 2000) |
| immunodeficiency with hypoparathyroidism | diGeorge syndrome |
| immunodeficient | Those diseases in which immune reactions are suppressed or reduced. Reasons may include congenital absence of B and/or T lymphocytes or viral killing of helper lymphocytes (see HIV). (18 Nov 1997) |
| immunodepressant | <immunology, pharmacology> An agent capable of suppressing immune responses. (18 Nov 1997) |
| immunodepression | See immunosuppression. (12 Dec 1998) |
| immunodepressor | <immunology, pharmacology> An agent capable of suppressing immune responses. (18 Nov 1997) |
| immunodiagnosis | The process of determining specified immunologic characteristics of individuals or of cells, serum, or other biologic specimens. (05 Mar 2000) |
| immunodiagnostic | A medical diagnostic based on the highly specific interaction between an antibody and an antigen. The antibody is used to detect the presence of the antigen. Monoclonal antibodies have come to be used in over 20 percent of all medical diagnostic procedures. (14 Nov 1997) |
| immunodiffusion | <technique> The classical technique used to detect the presence of antibodies and determine their specificity by visualisation of precipitin lines. A technique for analysing antigen and antibody mixtures by watching them as they diffuse toward each other within a support medium (usually a gel). The precipitin lines (precipitated antigen-antibody complexes) form where the binding concentrations of antigen and antibody are equivalent. Patient serum diffuses from one well through the gel and reacts with a known specific antigen (or antibody) which diffuses through the gel from a second well. Immunodiffusion is strictly qualitative, although the density of the precipitin line and the distance of the line from the sample well may give some indication of the antibody concentration. Synonym: double diffusion, Ouchterlony technique. (01 Dec 1998) |
| immunodominant epitopes | Subunits of the antigenic determinant that are most easily recognised by the immune system and thus most influence the specificity of the induced antibody. (12 Dec 1998) |
| immunoelectron microscopy | <technique> A technique for using an electron microscope to locate specific antigensin cells or tissue. (09 Oct 1997) |
| immunoelectrophoresis | <technique> A two-step procedure which first involves the electrophoretic separation of proteins, followed by the linear diffusion of antibodies into the electrophoretic gel from a trough which extends through the length of the gel adjacent to the electrophoretic path. The antigen-antibody reactions produce precipitin arcs at positions where equivalence occurs. Although quantitation is subjective, an experienced eye candetermine not only the presence of the antigen but, through visual comparison to normal control sera, may discriminate relative increases or decreases of antigen by gauging the length and density of the precipitin arcs at positions established for specific antigens using known standards. (01 Dec 1998) |