| multiple intestinal polyposis | Begins usually in late childhood; polyps increase in numbers, causing symptoms of chronic colitis, and carcinoma of the colon almost invariably develops in untreated cases; autosomal dominant inheritance. In the Gardner syndrome there are extracolonic changes (desmoid tumours, etc.). Synonym: polyposis coli. Hamartomatous polyposis of the small or large intestine, Peutz-Jeghers syndrome with melanin spots on the lips, less common, miscellaneous, rare, and doubtful occurrences. Synonym: familial intestinal polyposis. (05 Mar 2000) |
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| multiple lentigines syndrome | <syndrome> An autosomal dominant inherited disorder characterised by freckle-like spots (lentigines) on the trunk. Other findings may include wide set eyes, sternum abnormalities, prominent ears, deafness, cafe-au-lait spots, pulmonary stenosis, cryptorchidism, delayed puberty or hypogonadism. There is no treatment available only underlying management of each problem. Inheritance: autosomal dominant. (27 Sep 1997) |
| multiple lipoprotein-type hyperlipidaemia | <biochemistry> Inherited as a defective gene, this disorder is characterised by elevations in serum cholesterol and/or triglycerides. There are often multiple types of lipoproteins (LDL) elevated in one family. This condition is associated with an increased risk of cardiovascular disease. Origin: Gr. Haima = blood (27 Sep 1997) |
| multiple mucosal neuroma syndrome | <syndrome> Multiple submucosal neuromas or neurofibromas of the tongue, lips, and eyelids in young persons; sometimes associated with tumours of the thyroid or adrenal medulla, or with subcutaneous neurofibromatosis. (05 Mar 2000) |
| multiple myeloma | <oncology, tumour> See myeloma cell. (18 Nov 1997) |
| multiple myelomatosis | <oncology, tumour> See myeloma cell. (18 Nov 1997) |
| multiple myositis | The occurrence of multiple foci of acute inflammation in the muscular tissue and overlying skin in various parts of the body, accompanied by fever and other signs of systemic infection. See: dermatomyositis. Synonym: acute disseminated myositis, pseudotrichinosis, pseudotrichiniasis. (05 Mar 2000) |
| multiple neuritis | <neurology> A disease process involving a number of peripheral nerves. Origin: Gr. Pathos = disease (14 Oct 1997) |
| multiple organ failure | A progressive condition usually characterised by combined failure of the lungs, liver, kidney, and clotting mechanisms, usually postinjury or postoperative. (12 Dec 1998) |
| multiple parasitism | A condition in which parasites of different species parasitise a single host, in contrast to superparasitism or hyperparasitism. (05 Mar 2000) |
| multiple personality | A dissociative disorder in which two or more distinct conscious personality's alternately prevail in the same person, without any personality being aware of the other. See: dual personality. (05 Mar 2000) |
| multiple personality disorder | A dissociative disorder in which the individual adopts two or more distinct personalities. Each personality is a fully integrated and complex unit with memories, behaviour patterns and social friendships. Transition from one personality to another is sudden. (12 Dec 1998) |
| multiple pregnancy | Condition of bearing two or more foetuses simultaneously. Synonym: plural pregnancy, polycyesis. (05 Mar 2000) |
| multiple renal cysts | <radiology> Adult (autosomal-dominant) polycystic kidney disease, multiple simple cysts, tuberous sclerosis, von Hippel-Lindau syndrome, Meckel-Gruber syndrome (12 Dec 1998) |
| multiple sclerosis | <neurology> Neurodegenerative disease characterised by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in 3rd or 4th decade with intermittent progression over an extended period. Cause still uncertain. (18 Nov 1997) |