| 2-isopropylmalate synthase | <enzyme> An enzyme that catalyses the first step in the biosynthetic pathway to leucine, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. Chemical name: 3-Carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) Registry number: EC 4.1.3.12 (12 Dec 1998) |
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| 2-phosphinomethylmalic acid synthase | <enzyme> From streptomyces hygroscopicus; catalyses the condensation of phosphinopyruvic acid and acetyl-CoA to form phosphinomethylmalic acid Registry number: EC 4.1.3.- Synonym: pmm synthase (26 Jun 1999) |
| 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | <enzyme> E coli enzyme; catalyses formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate from 2-ketoglutarate and isochorismate; requires thiamine pyrophosphate and liberates pyruvate from the isochorismate molecule; see also o-succinylbenzoate synthase Registry number: EC 4.1.3.- Synonym: shchc synthase (26 Jun 1999) |
| 3-(2,4--dioxo-6-methyl-5-pyrimidinyl)acrylic acid synthase | <enzyme> Involved in sparsomycin biosynthesis; catalyses conversion of 3-(4-oxo-6-methyl-5-pyrimidinyl)acrylic acid to 3-(2,4-dioxo-6-methyl-5-pyrimidinyl)acrylic acid Registry number: EC 1.14.13.- Synonym: (e)-uca synthase (26 Jun 1999) |
| lactose synthase | <enzyme> An enzyme of the transferase class that catalyses the transfer of galactose from udpgalactose to glucose, forming lactose. The enzyme is a complex of the enzyme n-acetyllactosamine synthase and alpha-lactalbumin; the latter protein is present in lactating mammary gland cells where it alters the usual specificity of the former to make lactose synthesis the preferred reaction. Chemical name: UDPgalactose:D-glucose 4-beta-D-galactosyltransferase Registry number: EC 2.4.1.22 (12 Dec 1998) |
| 3-oxoacyl-ACP synthase | <enzyme> An enzyme condensing malonyl-ACP and acyl-cys-protein to 3-oxoacyl-ACP + cys-protein + CO2, and similar reactions, as steps in fatty acid synthesis; cys-protein is also a part of the fatty acid synthase complex. Synonym: acyl-malonyl-ACP synthase, beta-ketoacyl-ACP synthase. (05 Mar 2000) |
| 3-oxoacyl-(acyl-carrier-protein) synthase | <enzyme> An enzyme of long-chain fatty acid synthesis, that adds a two-carbon unit from malonyl-(acyl carrier protein) to another molecule of fatty acyl-(acyl carrier protein), giving a beta-ketoacyl-(acyl carrier protein) with the release of carbon dioxide. Chemical name: Acyl-(acyl carrier protein):malonyl-(acyl-carrier-protein) C-acyltransferase (decarboxylating) Registry number: EC 2.3.1.41 (12 Dec 1998) |
| 4-hydroxybenzoate synthase | <chemical> Complex associated with mitochondrial membranes of roots of cucumis sativus; converts p-coumaric acid to p-hydroxybenzoic acid; mechanism of multi-step reaction unclear Chemical name: synthase, p-hydroxybenzoate Synonym: para-hydroxybenzoate synthase, p-hydroxybenzoate synthase (26 Jun 1999) |
| 5-epi-aristolochene synthase | <enzyme> From tobacco; converts farnesyl diphosphate to phyloalexin capsidiol; mw 56,828 kD; a sesquiterpene cyclase Registry number: EC 2.5.1.- (26 Jun 1999) |
| 6,7-dimethyl-8-ribityllumazine synthase | <chemical> Converts 5-amino-6-ribitylamino-2,4(1h,3h)-pyrimidinedione plus ribose 5-phosphate to an aliphatic intermediate which is converted to 6,7-dimethyl-8-ribityllumazine Chemical name: synthase, 6,7-dimethyl-8-ribityllumazine Synonym: 6,7-dmrl synthase, lumazine synthase (26 Jun 1999) |
| 6'-deoxychalcone synthase | <enzyme> 4-coumaroyl-CoA and 3 malonyl-CoA gives isoliquiritigenin (6'-deoxychalcone); requires NADPH; may be same enzyme as EC 2.3.1.74 Registry number: EC 2.3.1.- Synonym: 6'-dxchs (26 Jun 1999) |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-7,8-dihydropteroate synthase | <chemical> Bifunctional enzyme involved in folate biosynthesis in plants; genbank y08611 (pisum sativum) Synonym: hppk-dhps, pppk-dhps, hydroxymethyldihydropterin-pyrophosphokinase-dihydropteroate synthase (26 Jun 1999) |
| 6-pyruvoyltetrahydropterin synthase | <enzyme> An enzyme that catalyses a step in the synthesis of tetrahydrobiopterin; a deficiency of this enzyme will result in one form of hyperphenylalaninaemia. Acronym: 6-PTS (05 Mar 2000) |
| 7-(adenosine-5-pyrophosphoryl)-D-sedoheptulose synthase | <enzyme> Transketolase-like enzyme; adpribose and fructose-6-phosphate yields 7-(adenosine-5'-pyrophosphoryl)-d-sedoheptulose Registry number: EC 2.2.- (26 Jun 1999) |
| 8-amino-7-oxononanoate synthase | <enzyme> Chemical name: 7-keto-8-aminopelargonic acid synthetase Registry number: EC 2.3.1.47 Synonym: 7-kap synthetase, 8-amino-7-oxopelargonate synthase, 7-oxo-8-aminononanoate synthase, biof gene product (26 Jun 1999) |