| broad beta disease | Hyperlipoproteinaemia characterised by increased plasma levels of LDL, beta-lipoproteins, pre-beta-lipoproteins, cholesterol, phospholipids, and triglycerides; hypertriglyceridemia induced by a high carbohydrate diet, and glucose tolerance is abnormal; frequent eruptive xanthomas and atheromatosis, particularly coronary artery disease; biochemical defect lies in apolipoproteins; there are many varieties. Synonym: carbohydrate-induced hyperlipaemia, dysbetalipoproteinaemia, familial hyperbetalipoproteinaemia and hyperprebetalipoproteinaemia, familial hypercholesterolaemia with hyperlipaemia. (05 Mar 2000) |
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| galactosylxylosylprotein 3-beta-galactosyltransferase | <enzyme> Catalyses the reaction of udpgalactose and 4-beta-d-(galactosyl-o-beta-d-xylosylprotein to yield udp and 3-beta-d-galactosyl-o-beta-d-xylosylprotein Registry number: EC 2.4.1.134 Synonym: galactosyltransferase II, (26 Jun 1999) |
| mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase | <enzyme> Transfers n-acetylglucosamine from udp-glcnac in beta 1-4 linkage to the d-mannose residue of glcnac beta 1-6 (glcnac beta 1-2)man alpha-r where r is 1-6 man beta-(ch2)8cooch3 on methyl; model for asparagine linked oligosaccharide Registry number: EC 2.4.1.- Synonym: n-acetylglucosaminyltransferase vi (26 Jun 1999) |
| mannosyl-glycoprotein endo-beta-n-acetylglucosaminidase | <enzyme> A group of related enzymes responsible for the endohydrolysis of the di-n-acetylchitobiosyl unit in high-mannose-content glycopeptides and glycoproteins. Chemical name: Glycopeptide-D-mannosyl-N(4)-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase Registry number: EC 3.2.1.96 (12 Dec 1998) |
| gene rearrangement, beta-chain T-cell antigen receptor | Ordered rearrangement of T-cell variable gene regions coding for the beta-chain of antigen receptors. (12 Dec 1998) |
| genes, T-cell receptor beta | DNA sequences encoding the beta chain of the T-cell receptor. The genomic organization of the tcr beta genes is essentially the same in all species and is similar to the organization of ig genes. (12 Dec 1998) |
| receptors, antigen, T-cell, alpha-beta | T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognise antigens only when presented in association with major histocompatibility (MHC) molecules. (12 Dec 1998) |
| receptors, transforming growth factor beta | Cell-surface proteins that bind transforming growth factor beta and trigger changes influencing the behaviour of cells. Two types of transforming growth factor receptors have been recognised. They differ in affinity for different members of the transforming growth factor beta family and in cellular mechanisms of action. Transforming growth factor alpha binds to the same receptors as epidermal growth factor (see receptors, epidermal growth factor-urogastrone). (12 Dec 1998) |
| carotene, beta | An antioxidant which protects cells against oxidation damage that can lead to cancer. Beta-carotene is converted, as needed, to vitamin A. Food sources of beta carotene include vegetables such as carrots, sweet potatoes, spinach and other leafy green vegetables; and fruit such as cantaloupes and apricots. Excessive carotene in the diet can temporarily yellow the skin, a condition called carotenaemia, commonly seen in infants fed largely mushed carrots. (12 Dec 1998) |
| glucan 1,3-beta-glucosidase | <enzyme> Chemical name: exo-1,3-beta-glucanase Registry number: EC 3.2.1.58 Synonym: beta-(1-3)-glucanase, exoglucanase, 1,3-beta-glucanase, antiviral tobacco protein gp35, exo-1,3 beta-d-glucosidase, exg1 gene product, exoglucanase II, beta-1,3-glucanase (26 Jun 1999) |
| glucan endo-1,3-beta-d-glucosidase | <enzyme> An enzyme that hydrolyzes 1,3-beta-d-glucosidic linkages in 1,3-beta-d-glucans including laminarin, paramylon, and pachyman. Chemical name: 1,3-beta-D-Glucan glucanohydrolase Registry number: EC 3.2.1.39 (12 Dec 1998) |
| glucosaminylgalactosylglucosylceramide beta-galactosyltransferase | <enzyme> Attaches galactose in a beta 1-3 bond to form the tetrasaccharide-ceramide Registry number: EC 2.4.1.86 Synonym: lc3 galactosyltransferase, udp-galactose-lc3 galactosyltransferase, lactotriosylceramide galactosyltransferase, glcnac beta1-3 gal beta1-4 glc beta1-cer galactosyltransferase, lactatriaosylceramide beta 1-3-galactosyltransferase (26 Jun 1999) |
| glucosylceramide beta-1-4-galactosyltransferase | <enzyme> Catalyses the formation of lactosylceramide from glucosylceramide and udp galactose; also uses dihexosides as acceptor Registry number: EC 2.4.1.- Synonym: udpgalactose ceramide monohexoside galactosyltransferase, glccer galactosyltransferase, galt-2, udpgalactose-glucosylceramide beta-1-4-galactosyltransferase (26 Jun 1999) |
| glycine-rich beta-glycoprotein | <enzyme> A glycine-rich, heat-labile beta-glycoprotein found in blood. It is a proactivator of complement 3 in the alternate pathway of complement activation. Factor b is converted by factor d to c3 convertase. Registry number: EC 3.4.21.47 (12 Dec 1998) |
| glycine-rich beta-glycoproteinase | <enzyme> A serum protein which during the alternate pathway of complement activation converts the inactive properdin factor b to c3 convertase. Registry number: EC 3.4.21.46 (12 Dec 1998) |
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