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Aldara trademark for a preparation of imiquimod.
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aldaric acid any of various dicarboxylic acids resulting from oxidation of both terminal groups of an aldose to carboxyl groups, such as glutaric acid.
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aldehyde dehydrogenase (NAD+) [EC 1.2.1.3] an enzyme of the oxidoreductase class that catalyzes the oxidation of various aldehydes, using NAD+ as an electron acceptor, including the oxidation of acetaldehyde to acetate in the metabolism of ethanol. Multiple isozymes exist and deficiencies of the cytosolic or mitochondrial isozymes of liver result in accumulation of acetaldehyde; such deficiencies, particularly prevalent in East Asians, manifest as facial flushing, vasodilation, and tachycardia after ethanol ingestion. Called also acetaldehyde dehydrogenase.
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aldehyde oxidase [EC 1.2.3.1] an enzyme of the oxidoreductase class that catalyzes the oxidation of aldehydes to the corresponding acids, generating a superoxide anion. It is a molybdoflavoprotein found in liver tissue, catalyzing the oxidation of a wide variety of heterocyclic compounds and xenobiotics. Activity of this enzyme is believed to be deficient in molybdenum cofactor deficiency.
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aldehyde reductase [EC 1.1.1.21] an enzyme of the oxidoreductase class that catalyzes the reduction of aldoses to form alditols, using NADPH as an electron donor. In galactosemia due to galactokinase deficiency, catalysis of the reduction of galactose to galactitol by aldehyde reductase in the lens of the eye results in cataract formation. Called also aldose reductase.
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