| zimbabwe | A republic in southern africa, east of zambia and botswana and west of mozambique. Its capital is harare. It was formerly called rhodesia and southern rhodesia. The region was under the administration of the british south africa company from 1889 to 1923 when it became a self-governing british colony. Zimbabwe was a member of the federation of rhodesia and nyasaland 1953-63. It was granted independence by the british in 1980 when it became zimbabwe. The name is from that of a famous archaeological site whose name is the bantu zimba we bahwe, (house of stones) from zimba, the plural of imba (house) + bahwe (stones). It refers to ruins comprising an acropolis with huge walls of monoliths fitted without mortar. (12 Dec 1998) |
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| zimeldine | <chemical> 3-(4-bromophenyl)-n,n-dimethyl-3-(3-pyridinyl)-2-propen-1-amine. An inhibitor of serotonin uptake formerly used in the treatment of depression in doses of 200-300 mg daily. It was withdrawn worldwide in september 1983 because of the risk of guillain-barre syndrome associated with its use. Pharmacological action: serotonin uptake inhibitors. Chemical name: 2-Propen-1-amine, 3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-, (Z)- (12 Dec 1998) |
| Zimmerlin's atrophy | A variety of hereditary progressive muscular atrophy in which the atrophy begins in the upper half of the body. (05 Mar 2000) |
| Zimmerlin, Franz | <person> Swiss physician, 1858-1932. See: Zimmerlin's atrophy. (05 Mar 2000) |
| Zimmermann reaction | A chemical reaction between an alkaline solution of meta-dinitrobenzene and an active methylene group (carbon-16) of 17-ketosteroids; it is the basis of the 17-ketosteroid assay t.; more generally, a reaction between methylene ketones and aromatic polynitro compounds in alkaline solutions. Synonym: Zimmermann test. (05 Mar 2000) |
| Zimmermann test | A chemical reaction between an alkaline solution of meta-dinitrobenzene and an active methylene group (carbon-16) of 17-ketosteroids; it is the basis of the 17-ketosteroid assay t.; more generally, a reaction between methylene ketones and aromatic polynitro compounds in alkaline solutions. Synonym: Zimmermann test. (05 Mar 2000) |
| Zimmermann's corpuscle | <haematology> A discoid cell (3m diameter) found in large numbers in blood, important for blood coagulation and for haemostasis by repairing breaches (small breaks) in the walls of blood vessels. Platelet _ granules contain lysosomal enzymes, dense granules contain ADP (a potent platelet aggregating factor) and serotonin (a vasoactive amine). They also release platelet-derived growth factor which presumably contributes to later repair processes by stimulating fibroblast proliferation. Synonym: thrombocytes. (09 Oct 1997) |
| Zimmermann's elementary particle | <haematology> A discoid cell (3m diameter) found in large numbers in blood, important for blood coagulation and for haemostasis by repairing breaches (small breaks) in the walls of blood vessels. Platelet _ granules contain lysosomal enzymes, dense granules contain ADP (a potent platelet aggregating factor) and serotonin (a vasoactive amine). They also release platelet-derived growth factor which presumably contributes to later repair processes by stimulating fibroblast proliferation. Synonym: thrombocytes. (09 Oct 1997) |
| Zimmermann's granule | <haematology> A discoid cell (3m diameter) found in large numbers in blood, important for blood coagulation and for haemostasis by repairing breaches (small breaks) in the walls of blood vessels. Platelet _ granules contain lysosomal enzymes, dense granules contain ADP (a potent platelet aggregating factor) and serotonin (a vasoactive amine). They also release platelet-derived growth factor which presumably contributes to later repair processes by stimulating fibroblast proliferation. Synonym: thrombocytes. (09 Oct 1997) |
| Zimmermann, Karl | <person> German histologist, 1861-1935. See: Zimmermann's corpuscle, Zimmermann's granule, Zimmermann's elementary particle, polkissen of Zimmermann. (05 Mar 2000) |
| Zimmermann, Wilhelm | <person> German physician, *1910. See: Zimmermann reaction, Zimmermann test. (05 Mar 2000) |
| zinc | <chemistry, element> An essential trace element being an essential component of the active site of a variety of enzymes. Zinc has a high affinity for the side chains of cysteine and histidine. Zinc is present in tissues at levels of 0.1mM, but intracellular levels must be much lower. Abbreviation: Zn (18 Nov 1997) |
| zinc acetate | <chemical> A salt produced by the reaction of zinc oxide with acetic acid. It is used as a pharmaceutic necessity for zinc-eugenol cement and also as an astringent, styptic, and formerly as an emetic. Pharmacological action: astringents, pharmaceutic aid. (12 Dec 1998) |
| zinc arsenate | <chemical> A toxic compound of zinc and arsenic which is used as an insecticide and to preserve timber from decay. (11 May 1997) |
| zinc caprylate | A topical antifungal compound. (05 Mar 2000) |