| thymidylate synthase | <enzyme> An enzyme of the transferase class that catalyses the reaction 5,10-methylenetetrahydrofolate and dump to dihydrofolate and dtmp in the synthesis of thymidine triphosphate. Chemical name: 5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase Registry number: EC 2.1.1.45 (12 Dec 1998) |
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| thymidylate synthase-dihydrofolate reductase | <chemical> Bifunctional multienzyme complex purified from leishmania major Synonym: ts-dhfr, dhfr-ts (26 Jun 1999) |
| ectoine synthase | <enzyme> Catalyses cyclic condensation of n(gamma)-l-2,4-diaminobutyric acid to yield l-ectoine Registry number: EC 4.2.1.- Synonym: ectc gene product (26 Jun 1999) |
| endothelium-derived growth factor synthase | <enzyme> Converts l-arginine to a smooth muscle relaxing factor and stimulates the formation of cyclic-GMP Registry number: EC 1.5.1.- Synonym: edrf synthase (26 Jun 1999) |
| trehalose synthase | <enzyme> Catalyses the conversion of maltose into alpha,alpha-trehalose by intramolecular transglucosylation; mw about 62 kD; genbank d78198 Registry number: EC 2.4.1.- Synonym: tres gene product, tres enzyme (26 Jun 1999) |
| tRNA 2-selenouridine synthase | <enzyme> Catalyses the conversion of a 5-methylaminomethyl-2-thiouridine in trna to 5-methylaminomethyl-2-selenouridine Registry number: EC 2.8.1.- (26 Jun 1999) |
| tryptophan synthase | <enzyme> An enzyme that catalyses the conversion of l-serine and 1-(indol-3-yl)glycerol 3-phosphate to l-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyses the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. Chemical name: L-Serine hydro-lyase (adding indoleglycerol-phosphate) Registry number: EC 4.2.1.20 (12 Dec 1998) |
| farnesylgeranyl diphosphate synthase | <enzyme> A prenyltransferase which synthesises c25-prenyl diphosphate; distinct from geranylgeranyl diphosphate synthase (EC 2.5.1.29); can use geranylgeranyl diphosphate as a substrate Registry number: EC 2.5.1.- Synonym: fgpp synthase (26 Jun 1999) |
| UMP synthase | Uridine esterified by phosphoric acid on one or more sugar hydroxyl groups; UMP is typically uridine 5'-monophosphate; 2' and 3' derivatives also occur; precursor for the biosynthesis of other pyrimidine nucleotides. Synonym: UMP synthase, uridine 5'-monophosphate. Uridylic acid synthase, a bifunctional enzyme that contains the activities of both orotate phosphoribosyltransferase and orotidine-5'-monophosphate decarboxylase; catalyses a key step in pyrimidine biosynthesis; a deficiency of this enzyme leads to orotic aciduria. (05 Mar 2000) |
| fatty acid 2-chloroethyl ester synthase | <enzyme> Catalyses the formation of 2-chloroethyl esters of long-chain fatty acids; localised in the microsomal fraction of rat liver Registry number: EC 2.3.1.- Synonym: facees, 2-chloroethyl ester synthase (26 Jun 1999) |
| fatty acid synthase complex | The multienzyme complex that catalyses the formation of palmitate from acetylcoenzyme A, malonylcoenzyme A, and NADPH. (05 Mar 2000) |
| fatty acyl ethyl ester synthase | <enzyme> Myocardial enzyme; esterifies free fatty acids in the absence of ATP and coenzyme a; the fatty acid ethyl ester synthase III has homology with glutathione s-transferase Registry number: EC 2.3.1.- Synonym: fatty acid ethyl ester synthase, fatty acid ethyl ester synthase III, faee synthase, faees-iii gene product (26 Jun 1999) |
| uridine 5'-monophosphate synthase | <chemical> Consists of orotate phosphoribosyltransferase EC 2.4.2.10 and orotidylate decarboxylase EC 4.1.1.23 Chemical name: synthase, uridylate Synonym: ump synthase, uridine 5'-phosphate synthase, uridylate synthase (26 Jun 1999) |
| uroporphyrinogen-III synthase | <enzyme> An enzyme that catalyses the cyclization of hydroxymethylbilane to yield uroporphyrinogen III and water. Chemical name: Hydroxymethylbilane hydro-lyase (cyclizing) Registry number: EC 4.2.1.75 (12 Dec 1998) |
| flavonol synthase | <enzyme> Isolated from petunia hybrida; catalyses the dehydrogenation of dihydroflavonols to flavonols Registry number: EC 1.3.- Synonym: fls gene product (26 Jun 1999) |