| DEBS | dominant epidermolysis bullosa simplex |
|---|---|
| EBS | elastic back strap; electric brain stimulation; Emergency Bed Service; epidermolysis bullosa simplex... |
| HSG | herpex simplex genitalis; hysterosalpingogram, hysterosalpingography |
| LSC | late systolic click; left side colon cancer; left subclavian; lichen simplex chronicus; liquid scint... |
| TORCH | TOxoplasma, Rubella, Cytomegalovirus, Herpes, syphilis |
| circular DNA | <molecular biology> C.f. Linear DNA. Examples: plasmids, bacterial, mitochondrial, chloroplast and some viral genomes. (18 Nov 1997) |
|---|---|
| cloning, DNA | The use of DNA manipulation procedures to produce multiple copies of a single gene or segment of DNA. (12 Dec 1998) |
| molecules, recombinant DNA | A combination of DNA molecules of different origin that are joined using recombinant DNA technology. (12 Dec 1998) |
| competitor DNA | DNA from a test organism that is denatured and then used in in vitro hybridization experiments in which it competes with DNA (homologous) from a reference organism; used to determine the relationship of the test organism to the reference organism. (05 Mar 2000) |
| complementary DNA | <molecular biology> DNA that is synthesised from a messenger RNA template, the single-stranded form is often used as a probe in physical mapping to locate the gene or can be cloned in the double stranded form. Viral reverse transcriptase can be used to synthesise DNA that is complementary to RNA (for example an isolated mRNA). Acronym: cDNA (13 Nov 1997) |
| complementary DNA cloning | <molecular biology, technique> A lab technique where a double-stranded cDNA molecule (or dscDNA) is inserted into a cloning vector (another DNA molecule which will continue to be capable of replication after insertion of foreign material), so that the gene encoded by the cDNA can be expressed (transcribed and used) or so many copies of the gene can be made. (09 Oct 1997) |
| complementary DNA library | <molecular biology> A collection of all of the mRNA molecules present in a cell or organism, all turned into cDNA molecules with the enzyme reverse transcriptase, then inserted into vectors (other DNA molecules which can continue to replicate after addition of foreign DNA). The library can then be probed for the specific cDNA (and thus mRNA) of interest. (09 Oct 1997) |
| covalently closed circular DNA | <molecular biology> A circular molecule of double-stranded DNA which is supercoiled, or coiled up on itself due to internal tensions, because there are no breaks in the phosphate backbone (upon which the nucleotide bases are mounted) to relieve the tensions and allow it to form an open circle. (09 Oct 1997) |
| cytosine-DNA glycosidase | <enzyme> Acts on uv-irradiated DNA at modified cytosine residues which are not pyrimidine dimers Registry number: EC 3.2.2.- Synonym: cytosine-DNA glycosylase (26 Jun 1999) |
| hemimethylated DNA | <molecular biology> Duplex DNA where only one of the two strands are methylated and is important for regulating and protecting DNA. (13 Nov 1997) |
| satellite DNA | <molecular biology> DNA, usually containing highly repetitive sequences, that has a base composition (and thus density) sufficiently different from that of normal DNA that it sediments as a distinct band in caesium chloride density gradients. (18 Nov 1997) |
| Schizosaccharomyces pombe DNA endonuclease | <enzyme> Cleaves the phosphodiester bond immediately 5' of either cyclobutane pyrimidine dimers or 6-4 pyrimidine pyrimidones of uv-damaged DNA Registry number: EC 3.1.25.- Synonym: uv damage endonuclease, s. Pombe DNA endonuclease, uve1 gene product, spde (26 Jun 1999) |
| heteroduplex DNA | <molecular biology> This is DNA that contains complementary strands from two different DNA molecules with similar sequences. (09 Oct 1997) |
| highly repetitive DNA | <molecular biology> The fraction of the eukaryotic genome which consists of a short sequence of nucleotides that is repeated thousands of times all over the genome. Highly repetitive DNA is very similar to satellite DNA. (09 Oct 1997) |
| PspPI DNA methyltransferase | <enzyme> Methylates first cytosine in ggncc Registry number: EC 2.1.1.- Synonym: psppi methyltransferase, mtase (psppi), psppim gene product (26 Jun 1999) |