| chronic discoid lupus erythematosus | A form of lupus erythematosus in which cutaneous lesions are present; these commonly appear on the face and are atrophic plaques with erythema, hyperkeratosis, follicular plugging, and telangiectasia; in some instances systemic lupus erythematosis may develop. Synonym: chronic discoid lupus erythematosus. (05 Mar 2000) |
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| chronic disease | Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (12 Dec 1998) |
| chronic dysentery of cattle | A disease occurring in cattle and sheep, usually manifested by thickening of the wall of the intestine, particularly of the ileum; caused by infection with Mycobacterium paratuberculosis. Synonym: chronic dysentery of cattle, paratuberculosis. (05 Mar 2000) |
| chronic eczema | Thickening of skin with accentuated skin lines in eczema. Synonym: chronic eczema, eczema hypertrophicum. (05 Mar 2000) |
| chronic eosinophilic pneumonia | <radiology> Idiopathic, associated with allergies and desensitization, variant of Loeffler pneumonia, treatment: corticosteroids Findings: reverse pulmonary oedema pattern (= Loeffler's), areas of consolidation persists (days to weeks) see: eosinophilic lung disease (12 Dec 1998) |
| chronic familial icterus | <haematology> A hereditary disorder that leads to a chronic haemolytic anaemia due to an abnormality in the red blood cell membrane. This disorder is caused by a defective gene. Red cells are resistant to stress and rupture easily. Infants may appear jaundiced and pale. Fatigue, weakness and shortness of breath are other symptoms that may be seen in older patients. The spleen may also be enlarged. Treatment includes splenectomy (removal of the spleen). After this is accomplished the life-span of the red blood cells returns to normal. (27 Sep 1997) |
| chronic familial jaundice | <haematology> A hereditary disorder that leads to a chronic haemolytic anaemia due to an abnormality in the red blood cell membrane. This disorder is caused by a defective gene. Red cells are resistant to stress and rupture easily. Infants may appear jaundiced and pale. Fatigue, weakness and shortness of breath are other symptoms that may be seen in older patients. The spleen may also be enlarged. Treatment includes splenectomy (removal of the spleen). After this is accomplished the life-span of the red blood cells returns to normal. (27 Sep 1997) |
| chronic familial polyneuritis | Inflammation of nerves related to infiltration by amyloid. (05 Mar 2000) |
| chronic fatigue syndrome | <syndrome> An unusual illness, of uncertain cause, that is characterised by unexplained fatigue, weakness, muscle pain, lymph node swelling and malaise. (27 Sep 1997) |
| chronic fibrosing alveolitis | <radiology> Aka: usual interstitial pneumonia (UIP), 5-6th decade; M:F = 1:1, clubbing of fingers (83%), lymphocytosis on lavage, increased occurence of bronchogenic CA, average survival of 4-6 years; 87% mortality CXR findings: occasional ground glass pattern in early stage of alveolitis, diffuse reticulations (60%) predominantly at bases, honeycombing, pleural effusion (4%); pleural thickening (6%), pneumothorax in 7% (late stage), progressive volume loss see: interstitial pulmonary fibrosis (12 Dec 1998) |
| chronic fibrous thyroiditis | A rare fibrous induration of the thyroid gland, with adhesion to adjacent structures, which may cause tracheal compression. Synonym: chronic fibrous thyroiditis, ligneous struma, ligneous thyroiditis, Riedel's disease, Riedel's struma. (05 Mar 2000) |
| chronic focal sclerosing osteomyelitis | A reaction of bone to a mild bacterial infection, often the result of a carious tooth, in persons with a high degree of tissue resistance; results in a localised radio-opacity. Synonym: focal condensing osteitis. (05 Mar 2000) |
| chronic follicular conjunctivitis | Indolent inflammation of the conjunctiva, with discrete follicles in fornices that may be infective, toxic, or irritant in nature. (05 Mar 2000) |
| chronic glaucoma | A disorder which is characterised by increased pressure within the eyeball. This occurs secondary to the chronic blockage of normal fluid circulation within the eye. Increased pressure within the eye can cause damage to the optic nerve and eventual blindness. Glaucoma is the leading cause of blindness. Symptoms include decreased vision, halos around lights (worse at night) and mild chronic headaches. Treatment is generally with beta-blocker eyedrops. (27 Sep 1997) |
| chronic glomerulonephritis | Glomerulonephritis that presents with persisting proteinuria, chronic renal failure, and hypertension, of insidious onset or as a late sequel of acute glomerulonephritis; the kidneys are symmetrically contracted and granular, with scarring and loss of glomeruli and the presence of tubular atrophy and interstitial fibrosis. Synonym: chronic nephritis. (05 Mar 2000) |