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NADPH methemoglobin reductase an enzyme of the erythrocytes that catalyzes the reduction of methemoglobin to hemoglobin via oxidation of NADH. The physiological significance of the enzyme is uncertain; no endogenous intermediate electron carrier has been found, although the enzyme can be activated if methylene blue or other artificial electron acceptor is introduced. Called also methemoglobin reductase (NADPH).
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NADPH oxidase a plasma membrane–associated enzyme complex that catalyzes the univalent reduction of oxygen using NADPH as an electron donor; the superoxide anion formed acts as an oxidant in the phagocyte microbicidal system, proceeding through a series of electron transfer reactions that form the respirator burst. Various genetic defects in the system result in chronic granulomatous disease.
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NADPH–cytochrome P-450 reductase NADPH–ferrihemoprotein reductase.
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NADPH–ferrihemoprotein reductase [EC 1.6.2.4] an enzyme of the oxidoreductase class that catalyzes the transfer of electrons to cytochromes via oxidation of NADPH. It is a flavoprotein (FMN, FAD) occurring in the endoplasmic reticulum and serving as the initial electron donor in reactions catalyzed by cytochrome P-450 monooxygenases (e.g., unspecific monooxygenase). It can also transfer electrons to cytochromes b and c. Called also NADPH–cytochrome P-450 reductase.
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NAD Nicotinamide Adenine Dinucleotide, a coenzyme involved in redox reactions.
Ãâó: www.snell-pym.org.uk/sarah/glossary.html
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