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lymphocyte function-associated antigen-1 A heterodimer molecule widely expressed on cells of haematopoietic origin. Cd11a antigen comprises the alpha chain and the CD18 antigen (antigens, CD18) the beta chain. Lfa-1 is a major receptor of T-cells, B-cells, and granulocytes. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by natural killer cells and granulocytes. Intracellular adhesion molecule-1 (icam-1) has been defined as a ligand for lfa-1.
(12 Dec 1998)
lymphogranuloma venereum antigen A sterile preparation of inactivated chlamydiae grown in the yolk sac of domestic fowl and used as an antigen in the Frei test.
(05 Mar 2000)
Lyt antigen A set of plasmalemmal surface glycoproteins on mouse T lymphocytes. Possession of Lyt 1 partly defines a T helper cell and of Lyt 2, 3 suppressor and cytotoxic cells. Formerly known as Ly antigens.
See: Lyb antigen.
(18 Nov 1997)
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